Product image of Ibuprofen Lysine Wrafton Laboratories (Ibuprofen Lysine) supplied by GNH India

Ibuprofen Lysine Wrafton Laboratories

Active Ingredient:
Ibuprofen Lysine
Origin:
EU

Ibuprofen Lysine Wrafton Laboratories (Ibuprofen Lysine)

Ibuprofen Lysine, the active ingredient in Ibuprofen Lysine Wrafton Laboratories, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It is used to relieve mild to moderate pain, reduce fever, and manage inflammatory conditions such as musculoskeletal discomfort.

GNH India supplies Ibuprofen Lysine Wrafton Laboratories as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wrafton Laboratories Limited

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Indications & Clinical Uses

Ibuprofen Lysine is an NSAID that reduces inflammation and pain by inhibiting prostaglandin synthesis.

  • Mild to moderate pain: provides analgesia for headaches, dental pain, or musculoskeletal aches.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammatory conditions: alleviates swelling and discomfort in musculoskeletal disorders such as sprains or osteoarthritis.

How It Works

  • Ibuprofen lysine exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This blockade reduces the conversion of arachidonic acid to prostaglandins, thereby decreasing inflammation, pain signaling, and fever generation at the site of tissue injury.

Side Effects

Ibuprofen Lysine may cause adverse reactions, ranging from frequent, mild events to rare but serious conditions.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of lightheadedness.
  • Rash: mild skin redness or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or hemorrhage in the stomach or intestines.
  • Severe allergic reaction: anaphylaxis, facial swelling, or difficulty breathing.
  • Liver injury: jaundice or elevated liver enzymes.
  • Kidney impairment: reduced urine output or swelling.

Precautions & Warnings

Before using Ibuprofen Lysine, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or history of GI bleeding.
  • Evaluate cardiovascular status: use cautiously in individuals with hypertension or heart disease.
  • Monitor renal function: consider dose adjustment in patients with impaired kidney function.
  • Avoid concomitant use with other NSAIDs or aspirin: increased risk of adverse effects.
  • Use during pregnancy and lactation only if clearly needed: limited safety data available.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen Lysine can interact with other medicines; awareness helps prevent complications.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • SSRIs or SNRIs: heightened chance of gastrointestinal bleeding.
  • Corticosteroids: additive risk of ulceration and GI bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may impair renal function when combined.
  • Lithium: ibuprofen can raise lithium levels, risking toxicity.
  • Methotrexate: reduced clearance may increase toxicity.

Frequently Asked Questions

Ibuprofen Lysine Wrafton Laboratories is an over‑the‑counter NSAID indicated for mild to moderate pain, fever, and inflammatory conditions such as musculoskeletal aches, sprains, or osteoarthritis. It works by reducing prostaglandin production, which helps alleviate discomfort and lower elevated body temperature.

Ibuprofen lysine non‑selectively inhibits the cyclooxygenase enzymes COX‑1 and COX‑2. By blocking these enzymes, it reduces the synthesis of prostaglandins, which are mediators of pain, fever, and inflammation. The lowered prostaglandin levels result in decreased sensation of pain, reduced fever, and diminished inflammatory swelling.

The appropriate dose of ibuprofen lysine is determined by the prescribing healthcare professional based on the individual’s age, weight, condition being treated, and other medical factors. Patients should follow the prescriber’s instructions and the product labeling without self‑adjusting the amount.

Safety data for ibuprofen lysine in pregnancy and lactation are limited. It should only be used during pregnancy or while breastfeeding if the potential benefit justifies the possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or nursing should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Ibuprofen lysine is a salt form of ibuprofen that dissolves more rapidly, potentially offering faster onset of pain relief compared with standard ibuprofen tablets. Both deliver the same active moiety and share similar efficacy and safety profiles, but the lysine salt may be preferred when quicker absorption is desired.

Ibuprofen lysine tablets should be stored at ambient temperature, below 25 °C, in their original packaging. Protect them from moisture, direct sunlight, and excessive heat to maintain product stability and potency throughout its shelf life.

Ibuprofen lysine is taken orally, usually with a glass of water. It can be taken with or without food, although taking it with food may lessen mild gastrointestinal discomfort. Patients should swallow the tablet whole and avoid crushing or chewing unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and kidney injury, especially in individuals with pre‑existing renal disease or dehydration. Patients should seek immediate medical attention if they notice signs of bleeding, severe rash, swelling, or sudden loss of kidney function.

Ibuprofen lysine should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers or bleeding, severe heart failure, uncontrolled hypertension, and those in the third trimester of pregnancy. It is also contraindicated in patients taking certain anticoagulants or other drugs that markedly increase bleeding risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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