Product image of Ibuprofen Marel (Ibuprofen) supplied by GNH India

Ibuprofen Marel

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Marel (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Marel, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as a tablet for oral use. It works by reducing pain, lowering fever, and diminishing inflammation associated with conditions such as arthritis, musculoskeletal injuries, and common colds, providing symptomatic relief for both adults and children under medical supervision.

GNH India supplies Ibuprofen Marel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality‑controlled batches that meet EU regulatory standards and reliable delivery timelines.

Manufacturer / TM Owner

Marel B.V.

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting prostaglandin synthesis.

  • Pain: provides analgesic relief for mild to moderate acute or chronic pain.
  • Fever: lowers elevated body temperature in febrile states.
  • Inflammation: decreases swelling and discomfort in inflammatory conditions such as arthritis.
  • Musculoskeletal injury: alleviates pain and inflammation from sprains, strains, and back pain.
  • Post‑operative discomfort: helps manage mild postoperative pain.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it diminishes peripheral sensitization of nociceptors, lowers fever set‑points in the hypothalamus, and limits inflammatory exudate formation, resulting in analgesic, antipyretic, and anti‑inflammatory actions.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal upset: includes stomach pain or discomfort.
  • Nausea: feeling of queasiness.
  • Dyspepsia: indigestion or heartburn.
  • Headache: mild to moderate head pain.
  • Dizziness: sensation of light‑headedness.
  • Rash: skin redness or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: may present as black stools or vomiting blood.
  • Ulcer perforation: a serious gastrointestinal emergency.
  • Renal impairment: reduced kidney function, especially with prolonged use.
  • Severe allergic reactions: such as anaphylaxis, requiring immediate medical attention.
  • Hepatotoxicity: liver injury indicated by jaundice or elevated enzymes.
  • Thrombocytopenia: low platelet count leading to easy bruising.

Precautions & Warnings

Before using Ibuprofen Marel, consider the following precautions to minimize risks.

  • Assess renal function: monitor kidney health in patients with pre‑existing renal disease.
  • Evaluate gastrointestinal risk: use the lowest effective dose in patients with a history of ulcers or bleeding.
  • Avoid in third trimester: contraindicated during late pregnancy due to fetal risks.
  • Use caution with anticoagulants: increased bleeding risk when combined with warfarin or similar agents.
  • Monitor liver enzymes: consider hepatic function during prolonged therapy.
  • Store at ambient temperature: keep below 25 °C, in the original pack, and protect from moisture.

Avoid Interactions

Ibuprofen can interact with other medicines; some combinations should be avoided while others require careful monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened risk of bleeding.
  • Lithium: ibuprofen may increase lithium serum concentrations.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Diuretics: may diminish antihypertensive effect.
  • Alcohol: combined use can increase gastrointestinal irritation.

Frequently Asked Questions

Ibuprofen Marel is used to relieve mild to moderate pain, reduce fever, and decrease inflammation associated with conditions such as arthritis, musculoskeletal injuries, and common colds. It provides symptomatic relief as part of a broader treatment plan prescribed by a healthcare professional.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are required for prostaglandin production. Lower prostaglandin levels reduce peripheral pain signaling, lower the hypothalamic set‑point for temperature, and limit inflammatory fluid accumulation.

The appropriate dose of Ibuprofen Marel is determined by the prescribing clinician based on the patient’s age, weight, the severity of symptoms, and any underlying medical conditions. Dosage recommendations follow local regulatory guidelines and should not be altered without professional advice.

Safety of ibuprofen during pregnancy and lactation is not fully established. It is generally avoided in the third trimester because of potential fetal risks, and caution is advised earlier in pregnancy. Breastfeeding mothers should consult their healthcare provider before use.

To order Ibuprofen Marel, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ibuprofen Marel shares the core anti‑inflammatory and analgesic properties of other NSAIDs but is distinguished by its well‑characterized safety profile, rapid onset of action, and availability in standard oral tablet form. Compared with agents like naproxen or diclofenac, ibuprofen generally has a shorter half‑life, which may affect dosing frequency.

Ibuprofen Marel tablets should be stored at ambient temperature, below 25 °C, in their original packaging to protect from moisture and light. Keep the container tightly closed and out of reach of children. Do not store in bathrooms or near heat sources.

Ibuprofen Marel is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort. The tablet should be swallowed whole and not chewed or crushed unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, renal impairment especially with prolonged use, and liver injury. Patients should seek immediate medical attention if they notice black stools, vomiting blood, severe rash, swelling of the face or throat, or sudden loss of urine output.

Ibuprofen Marel should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, or advanced renal or hepatic disease. It is also contraindicated in the third trimester of pregnancy and should be used with caution in patients on anticoagulant therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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