Product image of Ibuprofen Noridem (Ibuprofen) supplied by GNH India

Ibuprofen Noridem

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Noridem (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Noridem, is a nonsteroidal anti-inflammatory drug presented as an injectable solution for intravenous use. It is employed to manage pain, reduce fever, and control inflammation, including postoperative discomfort, in hospitalized patients and other clinical settings.

GNH India supplies Ibuprofen Noridem as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU quality standards. The product is manufactured under EU Good Manufacturing Practice and is available for intravenous administration in acute care environments.

Manufacturer / TM Owner

Noridem Enterprises Ltd

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Indications & Clinical Uses

  • Ibuprofen Noridem, an intravenous NSAID, is indicated for conditions where inflammation, pain or fever are present.
  • Pain: Provides rapid analgesia for moderate to severe acute pain, such as postoperative or trauma‑related pain.
  • Fever: Lowers elevated body temperature by acting on the hypothalamic heat‑regulation center.
  • Inflammation: Reduces inflammatory swelling in musculoskeletal or soft‑tissue injuries.
  • Postoperative pain: Controls pain following surgical procedures, facilitating early mobilization.

How It Works

  • Ibuprofen Noridem exerts its effect by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the conversion of arachidonic acid to prostaglandins, which are mediators of pain, fever and inflammation. By decreasing prostaglandin synthesis at the site of injury and in the central nervous system, the drug produces analgesic, antipyretic and anti‑inflammatory actions.

Side Effects

Intravenous ibuprofen may be associated with a range of adverse reactions, which are classified by frequency and severity.

Common Side Effects

  • Injection site pain: mild discomfort at the infusion site.
  • Nausea: feeling of queasiness.
  • Headache: mild to moderate head pain.
  • Dizziness: transient light‑headedness.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction with airway compromise.
  • Gastrointestinal bleeding: ulceration or hemorrhage in the GI tract.
  • Acute renal impairment: sudden decrease in kidney function.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis.

Precautions & Warnings

  • When using Ibuprofen Noridem, clinicians should observe several safety considerations to minimize risk.
  • Renal function: assess baseline kidney function and monitor during therapy.
  • Hepatic function: evaluate liver enzymes before and during treatment.
  • Cardiovascular risk: use the lowest effective dose in patients with heart disease.
  • Bleeding risk: avoid in individuals with active ulcers or coagulopathy.
  • Hypersensitivity: discontinue if signs of allergic reaction appear.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Ibuprofen Noridem can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • ACE inhibitors: may impair renal function.
  • Methotrexate: reduced clearance and potential toxicity.

Moderate Interactions (Monitor Closely)

  • SSRIs: additive bleeding risk.
  • Diuretics: possible reduction in antihypertensive effect.

Frequently Asked Questions

Ibuprofen Noridem is an intravenous formulation of ibuprofen used to treat moderate to severe pain, reduce fever, and control inflammation, including postoperative pain, in hospital or acute‑care settings.

Ibuprofen inhibits the cyclooxygenase enzymes COX‑1 and COX‑2, which reduces the synthesis of prostaglandins—chemical mediators that cause pain, fever, and inflammation—thereby providing analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Ibuprofen Noridem is determined by the prescribing clinician based on the patient’s condition, weight, renal function and other clinical factors. Dosage regimens are not standardized in public information.

Safety data for intravenous ibuprofen in pregnancy and lactation are limited. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and only under medical supervision.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Compared with oral ibuprofen, the intravenous form provides faster onset of analgesia and is useful when oral administration is not feasible. It offers a similar safety profile to other IV NSAIDs such as ketorolac, but dosing flexibility and renal considerations may differ.

Store the product at 2‑8 °C in a refrigerator, protect it from light, and do not freeze or shake the vial. Keep the solution in its original packaging until use to maintain sterility.

Ibuprofen Noridem is given by intravenous infusion. The solution is diluted according to the prescribing information and administered over the recommended time period, typically as a short infusion under clinical supervision.

Serious risks include anaphylactic reactions, gastrointestinal bleeding or ulceration, acute renal impairment, hepatic dysfunction, and cardiovascular events such as thrombotic complications. Patients should be monitored closely for these events.

Contraindications include known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal bleeding, severe renal or hepatic impairment, and patients with a history of severe cardiovascular disease where NSAIDs are discouraged.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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