Product image of Ibuprofen Ovaal Kruidvat (Ibuprofen) supplied by GNH India

Ibuprofen Ovaal Kruidvat

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Ovaal Kruidvat (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Ovaal Kruidvat, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats mild to moderate pain, fever and inflammation in adults and children when appropriate.
GNH India supplies Ibuprofen Ovaal Kruidvat as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies worldwide.

Manufacturer / TM Owner

Mae Holding Bv

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Indications & Clinical Uses

  • Ibuprofen acts on the cyclo‑oxygenase pathway to relieve symptoms associated with several common conditions.
  • Pain (mild to moderate): reduces discomfort from headaches, dental pain, musculoskeletal aches and minor injuries.
  • Fever: lowers elevated body temperature in acute febrile states.
  • Inflammation: diminishes swelling and tenderness in conditions such as arthritis or soft‑tissue injury.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis leads to diminished inflammation, lower fever, and decreased sensitisation of nociceptors, providing analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may range from mild to serious and should be monitored during therapy.

Common Side Effects

  • Nausea
  • Dyspepsia
  • Headache
  • Dizziness

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation
  • Severe allergic reaction (anaphylaxis)
  • Kidney function impairment

Precautions & Warnings

  • Before using ibuprofen, consider the following safety measures.
  • Assess renal function: adjust use in patients with kidney disease.
  • Avoid in active peptic ulcer disease: risk of gastrointestinal complications.
  • Use with caution in cardiovascular disease: may increase thrombotic risk.
  • Do not combine with other NSAIDs or aspirin without medical advice.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (warfarin, heparin): increased risk of bleeding.
  • SSRIs or SNRIs: heightened gastrointestinal bleeding risk.
  • Lithium: ibuprofen may raise lithium plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Methotrexate: reduced renal clearance may increase toxicity.
  • ACE inhibitors or ARBs: combined use may impair renal function, especially in dehydrated patients.

Frequently Asked Questions

Ibuprofen Ovaal Kruidvat is an over‑the‑counter NSAID indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, and arthritic swelling.

Ibuprofen blocks the activity of both COX‑1 and COX‑2 enzymes, which are required for the synthesis of prostaglandins. By lowering prostaglandin levels, it reduces inflammation, lowers body temperature, and diminishes the perception of pain.

The exact dose of ibuprofen is determined by the prescribing healthcare professional based on the individual’s age, weight, condition being treated, and overall health status. Patients should follow the prescriber’s instructions and the product label.

Safety of ibuprofen in pregnancy and lactation is not fully established. It is generally avoided in the third trimester and used only when the potential benefit outweighs the risk. Breastfeeding mothers should consult a healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Ibuprofen and naproxen belong to the same NSAID class and share similar mechanisms, but naproxen has a longer half‑life, allowing less frequent dosing. Ibuprofen often provides quicker onset of pain relief, while naproxen may be preferred for sustained anti‑inflammatory control. Choice depends on clinical judgment and patient tolerance.

Ibuprofen tablets should be stored at ambient temperature, below 25 °C, in the original container to protect them from moisture and direct sunlight. Keep out of reach of children and do not use if the packaging is damaged.

Ibuprofen is taken orally with a full glass of water. It may be taken with food or milk to lessen gastrointestinal irritation, but it can also be taken on an empty stomach if tolerated. Swallow tablets whole; do not crush or chew unless the product specifically allows it.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, kidney injury, and cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they notice signs of these conditions.

Ibuprofen should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, active peptic ulcer disease, severe renal or hepatic impairment, uncontrolled hypertension, and during the third trimester of pregnancy. Children under the recommended age for the specific formulation should also not use it.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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