Product image of Ibuprofen Ovaal Trekpleister (Ibuprofen) supplied by GNH India

Ibuprofen Ovaal Trekpleister

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Ovaal Trekpleister (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Ovaal Trekpleister, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats mild to moderate pain, fever and inflammation in adults and children as directed by a healthcare professional.

GNH India supplies Ibuprofen Ovaal Trekpleister as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mae Holding Bv

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Indications & Clinical Uses

  • Ibuprofen acts on inflammatory pathways to relieve a range of common conditions.
  • Pain: provides relief of mild to moderate acute pain such as headache, dental or musculoskeletal discomfort.
  • Fever: reduces elevated body temperature associated with infection or inflammation.
  • Inflammation: diminishes swelling and redness in conditions like sprains or minor injuries.
  • Arthritic conditions: alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its therapeutic effect by reversibly inhibiting cyclooxygenase‑1 and cyclooxygenase‑2 (COX‑1/COX‑2). This inhibition blocks the conversion of arachidonic acid to prostaglandins, leading to reduced synthesis of mediators that cause pain, fever, and inflammation.

Side Effects

Ibuprofen may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Gastrointestinal upset (nausea, dyspepsia)
  • Headache
  • Dizziness
  • Mild skin rash
  • Elevated blood pressure
  • Tinnitus

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe allergic reactions (anaphylaxis, angioedema)
  • Renal impairment or failure
  • Hepatotoxicity
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Cardiovascular events such as myocardial infarction or stroke

Precautions & Warnings

  • When using ibuprofen, consider the following safety measures.
  • Assess renal function: avoid or adjust use in severe renal impairment.
  • Evaluate gastrointestinal risk: use cautiously in patients with a history of ulcers or bleeding.
  • Consider cardiovascular risk: employ the lowest effective dose for the shortest duration.
  • Avoid in third‑trimester pregnancy: contraindicated due to fetal risks.
  • Monitor in asthma: may trigger bronchospasm in susceptible individuals.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function, especially in volume‑depleted patients.
  • Diuretics: potential for renal impairment when combined.
  • Lithium: ibuprofen can raise lithium serum concentrations, requiring monitoring.

Frequently Asked Questions

Ibuprofen Ovaal Trekpleister is an oral NSAID indicated for the temporary relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as headaches, dental pain, musculoskeletal injuries, and arthritic disorders.

Ibuprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. Lower prostaglandin levels result in decreased pain signaling, reduced fever, and less inflammation.

The appropriate dose is determined by a prescriber based on the patient’s age, weight, clinical condition, and response to therapy. Healthcare professionals follow local guidelines to select the strength and frequency that provide effective relief while minimizing risk.

Ibuprofen is generally avoided in the third trimester of pregnancy because of potential fetal complications. During the first and second trimesters, it should only be used if clearly needed and prescribed. It passes into breast milk in small amounts, so nursing mothers should consult a healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any temperature‑controlled requirements) and the necessary import documentation.

The primary alternative to ibuprofen is acetaminophen, which provides analgesic and antipyretic effects but lacks significant anti‑inflammatory activity. Ibuprofen offers stronger anti‑inflammatory action but carries higher gastrointestinal and renal risk, whereas acetaminophen is gentler on the stomach but can cause liver toxicity at high doses.

Store the tablets at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep out of reach of children and do not use if the packaging is damaged or the tablets appear discolored.

The product is taken orally with a full glass of water. It may be taken with or without food, although taking it with food can reduce the likelihood of stomach upset. Swallow the tablet whole; do not crush or chew unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment or failure, hepatotoxicity, and increased risk of cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged therapy.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients in the third trimester of pregnancy, and persons with severe renal or hepatic impairment should avoid using this medication unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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