Product image of Ibuprofen/Paracetamol 1 A Pharma (Ibuprofen, Paracetamol) supplied by GNH India

Ibuprofen/Paracetamol 1 A Pharma

Active Ingredient:
Ibuprofen, Paracetamol
Origin:
EU

Ibuprofen/Paracetamol 1 A Pharma (Ibuprofen, Paracetamol)

Ibuprofen, the active ingredient in Ibuprofen/Paracetamol 1 A Pharma, is a NSAID/Analgesic presented as a combined oral tablet for oral use. It is used to relieve pain, reduce fever, and manage inflammation in adults and children when appropriate, treating mild to moderate pain, fever, and musculoskeletal discomfort in a broad patient population.

GNH India supplies Ibuprofen/Paracetamol 1 A Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across global markets.

Manufacturer / TM Owner

1 A Pharma Gmbh

1
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Indications & Clinical Uses

Ibuprofen/Paracetamol is used to manage pain and fever through combined anti‑inflammatory and antipyretic mechanisms.

  • Pain: provides relief of mild to moderate nociceptive pain.
  • Fever: reduces elevated body temperature.
  • Headache: alleviates tension‑type and migraine‑associated headache.
  • Musculoskeletal pain: eases discomfort from strains, sprains and arthritic conditions.

How It Works

  • Ibuprofen inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, decreasing peripheral prostaglandin synthesis and producing anti‑inflammatory and analgesic effects. Paracetamol acts centrally to inhibit COX activity and modulate pain pathways, leading to analgesia and antipyresis. The combination yields complementary pain‑relieving and fever‑reducing actions without markedly increasing gastrointestinal toxicity when used at recommended doses.

Side Effects

Adverse reactions may occur with any medication. Most are mild and reversible.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or mild abdominal pain.
  • Dizziness or light‑headedness.
  • Headache.
  • Transient skin rash.
  • Mild elevation of liver enzymes.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Hepatic injury or jaundice.
  • Acute renal impairment or failure.
  • Anaphylactic or severe allergic reactions.
  • Hematologic abnormalities (e.g., thrombocytopenia).

Precautions & Warnings

Before using Ibuprofen/Paracetamol, consider the following safety measures.

  • Assess renal function: avoid in severe renal impairment.
  • Evaluate hepatic status: use with caution in liver disease.
  • Use the lowest effective dose: limit duration to reduce gastrointestinal risk.
  • Avoid concomitant NSAIDs: increased bleeding and ulcer risk.
  • Contraindicated in known hypersensitivity to ibuprofen or paracetamol.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen/Paracetamol can interact with other medicines; monitoring is advised.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Lithium: increased lithium serum concentrations.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive effect.
  • Diuretics: potential for reduced renal perfusion.
  • Alcohol: increased risk of liver injury and gastrointestinal irritation.

Frequently Asked Questions

Ibuprofen/Paracetamol 1 A Pharma is a combined oral tablet that provides analgesic, anti‑inflammatory, and antipyretic effects. It is commonly used to treat mild to moderate pain, reduce fever, and alleviate musculoskeletal discomfort such as strains, sprains, and arthritic pain.

Ibuprofen blocks cyclooxygenase enzymes (COX‑1 and COX‑2) in peripheral tissues, lowering prostaglandin production and reducing inflammation and pain. Paracetamol acts mainly in the central nervous system to inhibit COX activity and modulate pain pathways, producing analgesia and fever reduction. Together they provide complementary relief.

The specific dose and dosing schedule are determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Use of ibuprofen/paracetamol during pregnancy or lactation should only be considered when clearly needed and after consultation with a qualified healthcare provider. Ibuprofen is generally avoided in the third trimester, while paracetamol is regarded as relatively safe when used at recommended doses.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

The combination adds paracetamol’s central analgesic and antipyretic action to ibuprofen’s peripheral anti‑inflammatory effect. This can provide superior pain relief and fever control at lower individual doses of each component, potentially reducing the risk of dose‑related side effects compared with high‑dose ibuprofen alone.

Ibuprofen/Paracetamol 1 A Pharma tablets should be stored at ambient temperature, below 25 °C. Keep them in the original packaging, protect from moisture, heat, and direct sunlight, and ensure the container is tightly closed to maintain product stability.

The product is taken orally, usually with a full glass of water. It may be taken with or without food, but taking it with food can help minimise gastrointestinal discomfort. Swallow the tablet whole; do not crush or chew unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe skin reactions such as Stevens‑Johnson syndrome, hepatic injury, acute renal failure, and anaphylaxis. Patients should seek immediate medical attention if they notice signs of bleeding, rash, jaundice, reduced urine output, or difficulty breathing.

The product should be avoided in individuals with known hypersensitivity to ibuprofen, other NSAIDs, or paracetamol; in patients with active gastrointestinal ulceration or severe liver disease; and in those with severe renal impairment unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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