Product image of Ibuprofen/Paracetamol (Ibuprofen, Paracetamol) supplied by GNH India

Ibuprofen/Paracetamol

Active Ingredient:
Ibuprofen, Paracetamol
Origin:
EU

Ibuprofen/Paracetamol (Ibuprofen, Paracetamol)

Ibuprofen, the active ingredient in Ibuprofen/Paracetamol, is a NSAID/Analgesic combination presented as an oral tablet formulation for oral use. It provides pain relief and fever reduction for adults and children when appropriate.
GNH India supplies Ibuprofen/Paracetamol as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Ibuprofen/Paracetamol acts on inflammatory and pain pathways to relieve a range of common conditions.

  • Pain relief: reduces mild to moderate pain such as dental or postoperative discomfort.
  • Fever reduction: lowers elevated body temperature associated with infection.
  • Headache: alleviates tension‑type and mild migraine headaches.
  • Musculoskeletal pain: eases aches from strains, sprains or arthritis.

How It Works

  • Ibuprofen inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, decreasing peripheral prostaglandin synthesis and reducing inflammation and pain. Paracetamol acts centrally, likely through COX inhibition in the brain and modulation of serotonergic pathways, providing analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Dizziness or light‑headedness.
  • Headache.
  • Mild skin rash.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute liver injury, especially with overdose.
  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Anaphylaxis or severe allergic response.
  • Acute kidney injury, particularly in dehydrated patients.

Precautions & Warnings

Before using Ibuprofen/Paracetamol, consider the following safety measures.

  • Assess medical history: check for ulcers, kidney or liver disease, asthma, or cardiovascular risk.
  • Avoid concurrent NSAIDs: limit combined use to reduce gastrointestinal toxicity.
  • Limit alcohol intake: decreases risk of liver injury.
  • Use lowest effective dose: minimizes adverse events while achieving relief.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen/Paracetamol can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Lithium: ibuprofen may raise lithium plasma levels.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: potential impact on renal function.
  • Alcohol: enhances hepatotoxic potential of paracetamol.

Frequently Asked Questions

Ibuprofen/Paracetamol is an over‑the‑counter combination used to relieve mild to moderate pain and to reduce fever. It is commonly employed for headaches, dental pain, musculoskeletal aches, and febrile conditions associated with viral or bacterial infections.

The ibuprofen component blocks cyclooxygenase enzymes, lowering peripheral prostaglandin production and reducing inflammation. Paracetamol acts mainly in the central nervous system, inhibiting COX activity and influencing serotonergic pathways, which together provide analgesic and antipyretic effects.

The appropriate dose is determined by a healthcare professional based on the individual's age, weight, and clinical condition. Prescribers follow local guidelines to select the correct strength and frequency, ensuring safe and effective therapy.

Safety in pregnancy and lactation has not been fully established. Women who are pregnant, planning pregnancy, or breastfeeding should consult their physician before using this combination to weigh potential benefits against risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The combination offers dual mechanisms: ibuprofen provides anti‑inflammatory action while paracetamol adds central analgesia and fever control. This can achieve comparable pain relief with potentially lower individual doses, but it also introduces combined safety considerations such as gastrointestinal and hepatic risks.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging. Protect it from moisture, direct sunlight and excessive heat to maintain stability and potency throughout its shelf life.

The medication is taken orally with a full glass of water. It may be taken with or without food, although taking it with food can reduce the likelihood of stomach discomfort.

Serious adverse events include gastrointestinal bleeding or ulcer perforation, acute liver injury especially with overdose, severe skin reactions such as Stevens‑Johnson syndrome, anaphylactic allergic responses, and acute kidney impairment in susceptible individuals.

Individuals with known hypersensitivity to ibuprofen, paracetamol, or any component of the formulation should avoid it. It is also contraindicated in patients with active peptic ulcer disease, severe liver or kidney dysfunction, the third trimester of pregnancy, and in children for whom the dosage has not been established.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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