Ibuprofen/Paracetamol Mylan (Ibuprofen, Paracetamol)

The formulation combines two mechanisms: ibuprofen blocks cyclo‑oxygenase enzymes (COX‑1 and COX‑2) to lower peripheral prostaglandin production, reducing inflammation, pain and fever. Paracetamol primarily acts in the central nervous system, inhibiting a variant of COX activity and influencing the endocannabinoid system, which adds analgesic and antipyretic effects. Together they provide broader symptom control.

The appropriate dose of Ibuprofen/Paracetamol is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and local regulatory guidance. Healthcare professionals tailor the regimen to achieve optimal pain or fever control while minimizing risk, and patients should follow the specific instructions provided on the prescription label.

Safety in pregnancy and lactation depends on the trimester, maternal health, and existing medical conditions. Ibuprofen may be contraindicated in the third trimester, while paracetamol is generally considered safer. Women who are pregnant, planning pregnancy, or breastfeeding should consult their obstetrician or physician before using this combination to weigh benefits against potential risks.

To place an enquiry, visit the product page on gnhindia.com and submit the required quantity using the online form. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After submission, the sales team will verify trade or institutional credentials, then respond with pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Compared with ibuprofen alone, the addition of paracetamol can provide enhanced pain relief and fever reduction without a proportional increase in gastrointestinal side effects. Compared with paracetamol alone, the ibuprofen component adds anti‑inflammatory activity. The combination may allow lower individual doses of each agent, potentially improving tolerability while achieving comparable or superior efficacy for many acute pain scenarios.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children. Do not use the medication after the expiry date printed on the label, and discard any tablets that appear discoloured or damaged.

Ibuprofen/Paracetamol is intended for oral administration. The tablets should be swallowed whole with a full glass of water, preferably with food or milk to reduce potential stomach irritation. Patients should not crush, chew, or dissolve the tablets unless specifically instructed by a healthcare professional.

Serious adverse reactions, although uncommon, include gastrointestinal bleeding or ulceration, severe skin reactions such as Stevens‑Johnson syndrome, significant liver enzyme elevation or hepatitis, and acute kidney injury. Patients should seek immediate medical attention if they notice black stools, vomiting blood, unexplained jaundice, rash with blistering, or a sudden decrease in urine output.

The combination should be avoided in individuals with known hypersensitivity to ibuprofen, paracetamol, or any excipients in the tablet. It is also contraindicated in patients with severe renal or hepatic impairment, active peptic ulcer disease, uncontrolled heart failure, or those who are in the third trimester of pregnancy unless advised otherwise by a physician.