Product image of Ibuprofen/Paracetamol Sandoz (Ibuprofen, Paracetamol) supplied by GNH India

Ibuprofen/Paracetamol Sandoz

Active Ingredient:
Ibuprofen, Paracetamol
Origin:
EU

Ibuprofen/Paracetamol Sandoz (Ibuprofen, Paracetamol)

Ibuprofen and Paracetamol, the active ingredients in Ibuprofen/Paracetamol Sandoz, are NSAID/analgesic agents presented as oral tablets for oral use. They are combined to provide analgesic, antipyretic and anti‑inflammatory effects for adults and children when appropriate.
GNH India supplies Ibuprofen/Paracetamol Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz Hungária Kft

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Indications & Clinical Uses

Ibuprofen/Paracetamol works on pain and fever pathways, offering relief for several common conditions.

  • Mild to moderate pain: reduces discomfort from everyday aches and injuries.
  • Fever: lowers elevated body temperature.
  • Headache: alleviates tension‑type and mild migraine symptoms.
  • Musculoskeletal pain: eases soreness associated with strains, sprains and arthritis.

How It Works

  • Ibuprofen inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, decreasing prostaglandin synthesis and thereby reducing inflammation and peripheral pain signals. Paracetamol acts centrally by inhibiting COX activity in the brain and modulating serotonergic pathways, producing analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Adverse reactions may occur with oral ibuprofen/paracetamol combinations.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or mild abdominal pain.
  • Headache: transient worsening of headache.
  • Dizziness or light‑headedness.
  • Skin rash or mild itching.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling of face, lips or throat, difficulty breathing.
  • Hepatotoxicity: elevated liver enzymes or jaundice, especially with high paracetamol exposure.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Gastrointestinal bleeding or ulceration.

Precautions & Warnings

Use ibuprofen/paracetamol with awareness of potential risks and proper handling.

  • Assess liver function: avoid use in patients with known hepatic disease.
  • Evaluate kidney health: caution in renal impairment or dehydration.
  • Monitor for gastrointestinal issues: consider gastro‑protective measures in at‑risk individuals.
  • Avoid concurrent use of other NSAIDs or high‑dose paracetamol products.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen/Paracetamol can affect the activity of several other medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • High‑dose paracetamol products: risk of hepatotoxicity.
  • Certain antihypertensives (e.g., ACE inhibitors, diuretics): may reduce blood pressure control.

Moderate Interactions (Monitor Closely)

  • Lithium: ibuprofen may raise lithium levels.
  • Methotrexate: ibuprofen can increase toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): modestly heightened bleeding tendency.

Frequently Asked Questions

Ibuprofen/Paracetamol Sandoz is indicated for the relief of mild to moderate pain, reduction of fever, treatment of headache, and alleviation of musculoskeletal discomfort such as strains or arthritis‑related aches.

Ibuprofen blocks cyclooxygenase enzymes, lowering prostaglandin production and reducing inflammation. Paracetamol acts mainly in the central nervous system, inhibiting COX activity and influencing serotonergic pathways, which together provide analgesic and antipyretic effects.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition and any other medications being taken.

Safety in pregnancy and lactation has not been definitively established. Healthcare providers should evaluate the risk‑benefit ratio for each individual and consider alternative therapies when possible.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Combining ibuprofen with paracetamol can provide greater pain relief and fever reduction than ibuprofen alone, as the two agents act via complementary mechanisms—peripheral anti‑inflammatory action from ibuprofen and central analgesic/antipyretic activity from paracetamol.

Store the tablets at ambient temperature, below 25 °C, in the original packaging. Keep them away from moisture, heat and direct sunlight to maintain product stability.

The medication is taken orally, usually with a glass of water. It may be taken with or without food, but taking it with food can reduce gastrointestinal discomfort.

Serious risks include severe allergic reactions (anaphylaxis), liver injury from excessive paracetamol exposure, and gastrointestinal bleeding or ulceration, particularly in patients with pre‑existing risk factors.

Individuals with known hypersensitivity to ibuprofen, paracetamol, or any component of the formulation, as well as patients with severe liver disease, active gastrointestinal ulceration, or uncontrolled hypertension, should avoid this product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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