Product image of Ibuprofen Patheon (Ibuprofen) supplied by GNH India

Ibuprofen Patheon

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Patheon (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Patheon, is a nonsteroidal anti‑inflammatory drug presented as a standard tablet for oral use. It reduces pain, fever and inflammation in adults and children when prescribed by a healthcare professional.

GNH India supplies Ibuprofen Patheon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across markets. The company adheres to stringent manufacturing standards and provides reliable distribution to meet global demand.

Manufacturer / TM Owner

Patheon Softgels B.V.

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Indications & Clinical Uses

Ibuprofen is an NSAID that acts on the cyclooxygenase pathway to relieve various types of pain and inflammation.

  • Pain: Provides relief from mild to moderate acute pain such as headache, dental pain, or musculoskeletal discomfort.
  • Fever: Lowers elevated body temperature associated with infectious or inflammatory processes.
  • Inflammation: Reduces swelling and discomfort in conditions like sprains or strains.
  • Arthritis: Alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen inhibits the activity of cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which are key in the conversion of arachidonic acid to prostaglandins. By decreasing prostaglandin synthesis, it reduces inflammation, pain signaling, and fever generation at sites of tissue injury.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Rash or mild skin irritation.
  • Elevated blood pressure.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reactions: anaphylaxis, angioedema.
  • Hepatotoxicity or liver enzyme elevation.
  • Renal impairment or acute kidney injury.
  • Cardiovascular events: myocardial infarction or stroke.

Precautions & Warnings

When prescribing ibuprofen, clinicians should consider several precautionary measures to minimize risks.

  • Assess renal function: avoid use in patients with severe kidney disease.
  • Evaluate gastrointestinal risk: use with caution in those with a history of ulcers or bleeding.
  • Monitor cardiovascular status: limit use in patients with established heart disease.
  • Review concomitant medications: avoid concurrent use with other NSAIDs or anticoagulants without supervision.
  • Pregnancy and lactation: limit use during the third trimester and discuss risks with a healthcare provider.
  • Store at ambient temperature: keep below 25 °C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with other medicines, altering their effectiveness or increasing toxicity.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding risk.
  • ACE inhibitors or ARBs: may reduce antihypertensive effect and impair kidney function.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible reduction in diuretic efficacy and renal function.
  • Lithium: ibuprofen may raise lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.
  • Corticosteroids: additive risk of gastrointestinal ulceration.

Frequently Asked Questions

Ibuprofen Patheon is used to relieve mild to moderate pain, reduce fever, and diminish inflammation. It is commonly prescribed for conditions such as headaches, dental pain, musculoskeletal aches, fever associated with infections, and inflammatory disorders like arthritis.

Ibuprofen works by blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. Lower prostaglandin levels lead to reduced pain signaling, decreased inflammation, and a lower body temperature during fever.

The appropriate dose of ibuprofen Patheon is determined by the prescribing healthcare professional based on the patient’s age, weight, medical condition, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Ibuprofen should be used with caution during pregnancy, especially in the third trimester, because it may affect fetal cardiovascular development. While limited data exist for breastfeeding, short‑term use is generally considered compatible, but a healthcare provider should be consulted before use.

To order Ibuprofen Patheon, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Both ibuprofen and acetaminophen relieve pain and fever, but ibuprofen also has anti‑inflammatory properties because it inhibits COX enzymes. Acetaminophen lacks significant anti‑inflammatory activity and has a different safety profile, particularly regarding gastrointestinal and renal effects.

Ibuprofen Patheon should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and strong odors. Ensure the container is tightly closed to maintain product stability.

Ibuprofen Patheon is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort. The exact administration instructions are provided by the prescriber.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, kidney injury, liver toxicity, and cardiovascular events like heart attack or stroke. Patients should seek immediate medical attention if they experience symptoms such as severe stomach pain, vomiting blood, rash, or sudden shortness of breath.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, advanced kidney disease, or who are in the third trimester of pregnancy should avoid using Ibuprofen Patheon unless directed by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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