Product image of Ibuprofen Pfleger (Ibuprofen D,l-Lysinate) supplied by GNH India

Ibuprofen Pfleger

Active Ingredient:
Ibuprofen D,l-Lysinate
Origin:
EU

Ibuprofen Pfleger (Ibuprofen D,l-Lysinate)

Ibuprofen D,l-Lysinate, the active ingredient in Ibuprofen Pfleger, is a non‑steroidal anti‑inflammatory drug presented as an oral dosage form for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects and is indicated for the temporary relief of mild to moderate pain, fever and inflammatory conditions in the general population.

GNH India supplies Ibuprofen Pfleger as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide with a focus on quality assurance and regulatory compliance.

Manufacturer / TM Owner

Dr. Pfleger Arzneimittel Gmbh

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Indications & Clinical Uses

Ibuprofen Pfleger, an NSAID that inhibits prostaglandin synthesis, is used for several common conditions.

  • Pain: Provides temporary relief of mild to moderate pain such as headache, toothache, menstrual cramps, or musculoskeletal discomfort.
  • Fever: Reduces elevated body temperature associated with infections or inflammatory processes.
  • Inflammation: Decreases swelling and inflammation in conditions like minor sprains, strains, or arthritic flare‑ups.

How It Works

  • Ibuprofen D,l-Lysinate works by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are required for the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin production, it reduces the sensitization of nerve endings to pain, lowers the hypothalamic set‑point for temperature, and diminishes vascular permeability and leukocyte infiltration that contribute to inflammation.

Side Effects

Like other NSAIDs, Ibuprofen Pfleger may cause a range of adverse reactions, most of which are dose‑related and reversible.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or mild abdominal pain.
  • Headache: transient headache episodes.
  • Dizziness: occasional light‑headedness.
  • Rash: mild skin erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding: severe stomach or intestinal bleeding.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Hepatotoxicity: elevated liver enzymes or hepatitis.
  • Severe allergic reaction: anaphylaxis, angioedema, or bronchospasm.

Precautions & Warnings

When using Ibuprofen Pfleger, consider the following precautions to minimize risk.

  • Assess renal function: avoid use in patients with severe kidney disease or dehydration.
  • Monitor gastrointestinal risk: use with caution in individuals with a history of ulcers or bleeding.
  • Cardiovascular caution: limit use in patients with uncontrolled hypertension or heart failure.
  • Concomitant medications: review use with anticoagulants, other NSAIDs, or corticosteroids.
  • Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Ibuprofen Pfleger can interact with several medicines; awareness of major and moderate interactions helps ensure safe therapy.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • SSRIs: elevated bleeding risk.

Moderate Interactions (Monitor Closely)

  • Diuretics: may reduce antihypertensive effect.
  • Methotrexate: reduced renal clearance can increase toxicity.

Frequently Asked Questions

Ibuprofen Pfleger is an over‑the‑counter NSAID used to relieve mild to moderate pain, lower fever, and reduce inflammation associated with conditions such as headaches, toothaches, menstrual cramps, minor injuries, and arthritic flare‑ups.

Ibuprofen D,l-Lysinate inhibits the cyclooxygenase enzymes COX‑1 and COX‑2, which blocks the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin levels diminishes pain signaling, lowers body temperature, and curtails the inflammatory response.

The appropriate dose of Ibuprofen Pfleger is determined by a qualified prescriber based on the individual’s age, weight, medical condition, and response to therapy. Patients should follow the specific instructions provided on the product label or by their healthcare professional.

Safety of ibuprofen during pregnancy or lactation depends on the trimester and clinical circumstances. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using Ibuprofen Pfleger to weigh potential benefits against risks.

To order Ibuprofen Pfleger, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen Pfleger and naproxen belong to the same NSAID class and share similar mechanisms of COX inhibition. Ibuprofen generally has a shorter half‑life, requiring more frequent dosing, while naproxen provides longer‑lasting relief. Choice between them depends on patient tolerance, dosing convenience, and specific clinical considerations.

Ibuprofen Pfleger should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, excessive heat and direct sunlight, and ensure the container is tightly closed to maintain stability.

Ibuprofen Pfleger is taken orally, usually with a full glass of water. It may be taken with or without food; taking it with food can help reduce mild gastrointestinal discomfort. Patients should swallow tablets whole and avoid crushing or chewing them unless directed otherwise.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and renal or hepatic impairment. Patients should seek immediate medical attention if they experience black stools, vomiting blood, sudden swelling, difficulty breathing, or marked changes in urine output.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or advanced renal or hepatic disease should avoid Ibuprofen Pfleger unless specifically advised by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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