Product image of Ibuprofen Pharmaclan Modafen (Ibuprofen) supplied by GNH India

Ibuprofen Pharmaclan Modafen

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Pharmaclan Modafen (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Pharmaclan Modafen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve pain, reduce fever, and lessen inflammation in adults and children when appropriate.
GNH India supplies Ibuprofen Pharmaclan Modafen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Ibuprofen Pharmaclan Modafen belongs to the NSAID class and works by inhibiting prostaglandin synthesis, which is central to pain, fever and inflammatory pathways.

  • Pain: provides analgesic relief for mild to moderate acute pain such as headache, dental or musculoskeletal discomfort.
  • Fever: reduces elevated body temperature associated with infections or inflammatory conditions.
  • Inflammation: diminishes swelling and redness in conditions like arthritis or soft‑tissue injury.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This inhibition decreases the conversion of arachidonic acid to prostaglandins, thereby lowering the mediators responsible for pain sensation, fever generation, and inflammatory swelling.

Side Effects

Adverse reactions may range from mild to severe, depending on individual susceptibility and dosage.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: transient mild to moderate headache.
  • Dizziness: occasional light‑headedness or vertigo.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Renal impairment, especially in patients with pre‑existing kidney disease.
  • Severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome.
  • Hepatic enzyme elevation indicating possible liver injury.
  • Cardiovascular events including increased risk of thrombotic events.

Precautions & Warnings

Before using Ibuprofen Pharmaclan Modafen, consider the following safety measures.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding before initiating therapy.
  • Monitor renal function: especially in patients with chronic kidney disease or dehydration.
  • Use the lowest effective dose: limit duration to the shortest period needed for symptom control.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Take with food or milk: helps reduce stomach irritation.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen may interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Systemic corticosteroids: additive risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion, especially in volume‑depleted patients.
  • Diuretics: potential for reduced kidney function and electrolyte imbalance.

Frequently Asked Questions

Ibuprofen Pharmaclan Modafen is indicated for the relief of mild to moderate pain, reduction of fever, and control of inflammation associated with conditions such as headache, dental pain, musculoskeletal discomfort, and arthritic disorders. It works by targeting the underlying biochemical pathways that generate these symptoms.

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins. By lowering prostaglandin levels, it reduces the signals that cause pain, elevate body temperature, and promote inflammation, providing symptomatic relief.

The appropriate dose of Ibuprofen Pharmaclan Modafen is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Dosage recommendations are individualized and should follow the prescriber’s instructions.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and clinical circumstances. Generally, ibuprofen is avoided in the third trimester due to potential fetal risks, and caution is advised during the first two trimesters. Breastfeeding mothers should consult their physician, as small amounts may pass into milk.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Ibuprofen shares the core mechanism of COX inhibition with other NSAIDs, offering a balance of analgesic, antipyretic, and anti‑inflammatory effects. Compared with agents like naproxen or diclofenac, ibuprofen has a relatively shorter half‑life, which may allow for flexible dosing but may also require more frequent administration for sustained control.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging to protect from moisture and direct sunlight. Do not store in a bathroom or near heat sources, and keep out of reach of children.

Ibuprofen Pharmaclan Modafen is taken orally, usually with a full glass of water. It can be swallowed with or without food; however, taking it with meals or milk may lessen gastrointestinal discomfort. Follow the prescriber’s guidance on timing and frequency.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and cardiovascular events like myocardial infarction or stroke, particularly with high‑dose or prolonged use. Patients should be monitored for signs of these conditions and seek immediate medical attention if they occur.

Individuals with a known hypersensitivity to ibuprofen or any NSAID, those with active gastrointestinal ulceration or bleeding, severe heart failure, or advanced renal disease should avoid this medication. It is also contraindicated in patients taking certain anticoagulants or other NSAIDs without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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