Product image of Ibuprofen Pharmaclan Pharmaclan (Ibuprofen) supplied by GNH India

Ibuprofen Pharmaclan Pharmaclan

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Pharmaclan Pharmaclan (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Pharmaclan, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It provides analgesic, antipyretic, and anti‑inflammatory effects and is commonly used in adults and children for a variety of short‑term conditions.

GNH India supplies Ibuprofen Pharmaclan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and offers reliable global distribution, ensuring timely delivery across EU and other regulated markets.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Ibuprofen reduces prostaglandin synthesis and is indicated for several pain‑related and inflammatory conditions.

  • Pain: Provides analgesic relief for mild to moderate pain.
  • Fever: Lowers elevated body temperature in febrile states.
  • Inflammation: Decreases swelling and redness associated with acute inflammation.
  • Arthritis: Alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.
  • Dysmenorrhea: Relieves menstrual cramps and associated discomfort.
  • Headache: Treats tension‑type and mild migraine headaches.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, blocking the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis diminishes inflammation, pain signaling, and fever generation throughout the body.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea: Stomach upset or queasiness.
  • Dyspepsia: Indigestion or heartburn.
  • Headache: New or worsening head pain.
  • Dizziness: Light‑headed sensation.
  • Diarrhoea: Loose stools.
  • Rash: Mild skin irritation.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: Blood in stool or vomit.
  • Peptic ulcer: Persistent stomach pain or ulceration.
  • Renal impairment: Decreased urine output or swelling.
  • Severe allergic reaction: Hives, swelling of face or throat, difficulty breathing.
  • Stevens‑Johnson syndrome: Blistering skin rash.
  • Hepatic injury: Jaundice or abnormal liver tests.

Precautions & Warnings

When using ibuprofen, consider the following precautions to minimize risk.

  • Assess renal function: Use with caution in patients with kidney disease.
  • Evaluate cardiovascular risk: Avoid high‑dose or long‑term use in patients with heart disease.
  • Use lowest effective dose: Limit duration to the shortest period needed for symptom control.
  • Avoid in third‑trimester pregnancy: Potential risk to the fetus.
  • Monitor for gastrointestinal symptoms: Watch for signs of ulcer or bleeding.
  • Store at room temperature: Keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with other medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin, DOACs): Increased risk of bleeding.
  • Other NSAIDs or aspirin: Additive gastrointestinal toxicity.
  • Corticosteroids: Heightened risk of gastrointestinal ulceration.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: May reduce renal function, especially in dehydrated patients.
  • Methotrexate: Ibuprofen can decrease clearance, raising the potential for toxicity.

Frequently Asked Questions

Ibuprofen Pharmaclan is an oral NSAID indicated for the temporary relief of mild to moderate pain, reduction of fever, and mitigation of inflammation. It is commonly employed in conditions such as headache, dental pain, musculoskeletal aches, arthritis, dysmenorrhea, and febrile illnesses. The product is intended for short‑term use under the guidance of a healthcare professional.

Ibuprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. Prostaglandins mediate pain, fever, and inflammation; therefore, their reduction leads to analgesic, antipyretic, and anti‑inflammatory effects throughout the body.

The appropriate dose of Ibuprofen Pharmaclan is determined by the prescribing clinician based on the patient’s age, weight, condition being treated, and overall health status. Typical adult regimens range from 200 mg to 400 mg taken every 4‑6 hours, not exceeding the maximum daily limit, but exact dosing must follow the prescriber’s instructions.

Ibuprofen’s safety in pregnancy is not fully established; it is generally avoided in the third trimester because of potential fetal risks. During the first and second trimesters, it may be used only if the benefit outweighs the risk and after consulting a healthcare provider. Ibuprofen passes into breast milk in small amounts; nursing mothers should seek medical advice before use.

To order Ibuprofen Pharmaclan, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details (including any cold‑chain requirements if applicable), and assists with import documentation.

Ibuprofen belongs to the NSAID class, offering both analgesic and anti‑inflammatory actions, whereas acetaminophen (paracetamol) provides pain relief and fever reduction but lacks significant anti‑inflammatory effects. Compared with other NSAIDs such as naproxen or diclofenac, ibuprofen has a relatively short half‑life, allowing flexible dosing but may require more frequent administration for sustained relief.

Ibuprofen Pharmaclan should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments. Do not use the medication after the expiration date printed on the label.

Ibuprofen Pharmaclan is taken orally with a full glass of water. It may be taken with food or milk to lessen gastrointestinal discomfort, although it can also be taken on an empty stomach if tolerated. Swallow tablets whole; do not crush, chew, or split extended‑release forms unless specifically instructed by a healthcare professional.

Serious risks associated with ibuprofen include gastrointestinal bleeding or ulceration, cardiovascular events such as heart attack or stroke (especially with high‑dose or prolonged use), renal impairment leading to reduced urine output or swelling, and severe allergic reactions like anaphylaxis or Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice blood in stool, chest pain, sudden shortness of breath, or a rash with facial swelling.

Ibuprofen Pharmaclan should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active peptic ulcer disease, severe heart failure, uncontrolled hypertension, advanced renal or hepatic impairment, and in pregnant women during the third trimester. It is also contraindicated in patients taking certain anticoagulants or other NSAIDs without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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