Product image of Ibuprofen Pharmadev (Ibuprofen) supplied by GNH India

Ibuprofen Pharmadev

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Pharmadev (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Pharmadev, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides pain relief, reduces fever, and helps control inflammation in adults and children when appropriate.

GNH India supplies Ibuprofen Pharmadev as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pharmadev Healthcare Limited

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Indications & Clinical Uses

Ibuprofen acts on the cyclooxygenase pathway to alleviate symptoms associated with pain, fever and inflammation.

  • Pain relief: reduces mild to moderate nociceptive pain such as headache, dental or musculoskeletal discomfort.
  • Fever reduction: lowers elevated body temperature in febrile conditions.
  • Inflammation control: diminishes swelling and inflammatory response in conditions like arthritis or soft‑tissue injury.

How It Works

  • Ibuprofen inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, leading to decreased synthesis of prostaglandins that mediate pain, fever, and inflammation. By reducing prostaglandin levels, it blunts the peripheral sensitization of nociceptors and the central fever response, while also limiting inflammatory exudate formation.

Side Effects

Adverse reactions may range from mild to severe, depending on individual susceptibility and concomitant therapies.

Common Side Effects

  • Gastrointestinal discomfort: dyspepsia, heartburn, or mild nausea.
  • Headache: transient tension‑type headache.
  • Dizziness: occasional light‑headedness.
  • Skin rash: mild erythematous eruption.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding: potentially life‑threatening hemorrhage.
  • Renal impairment: acute kidney injury, especially in volume‑depleted patients.
  • Severe allergic reactions: anaphylaxis, angioedema, or Stevens‑Johnson syndrome.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess renal function: avoid or adjust dose in patients with significant kidney disease.
  • Evaluate gastrointestinal risk: use cautiously in individuals with a history of ulcer or bleeding.
  • Monitor cardiovascular status: limit use in patients with established heart disease or hypertension.
  • Avoid in third‑trimester pregnancy: contraindicated due to fetal risks.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • Corticosteroids: heightened ulcer risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may reduce renal perfusion, especially in dehydrated patients.
  • Diuretics: potential decrease in antihypertensive efficacy and renal function.

Frequently Asked Questions

Ibuprofen Pharmadev is an oral NSAID indicated for the relief of mild to moderate pain, reduction of fever, and control of inflammation associated with conditions such as musculoskeletal disorders, dental pain, and febrile illnesses. It is commonly prescribed when a non‑opioid analgesic is appropriate.

Ibuprofen works by inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin production, it reduces the sensitization of pain receptors, diminishes fever signaling in the hypothalamus, and limits the inflammatory cascade.

The appropriate dose of Ibuprofen Pharmadev is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

Ibuprofen is generally avoided in the third trimester of pregnancy because of potential fetal cardiovascular effects. Use during the first two trimesters should only occur if the prescriber deems it necessary. While limited data exist for breastfeeding, ibuprofen is excreted in small amounts in milk; clinicians should weigh benefits against possible risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifying trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Ibuprofen shares the same COX‑inhibiting mechanism as other NSAIDs such as naproxen or diclofenac, but it has a relatively short half‑life, which may require more frequent dosing for sustained effect. Its safety profile is comparable, though individual tolerability and specific contraindications (e.g., cardiovascular risk) guide the choice among agents.

Ibuprofen Pharmadev should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing in damp or excessively hot environments.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food or milk may reduce gastrointestinal discomfort. Swallow tablets whole; do not crush or chew unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, especially in patients with a history of ulcer disease or concurrent use of anticoagulants; renal impairment, which can be precipitated by dehydration or existing kidney disease; and severe hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome. Prompt medical attention is required if these occur.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulceration or bleeding, patients in the third trimester of pregnancy, and persons with severe uncontrolled heart failure or severe renal impairment should avoid using Ibuprofen Pharmadev unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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