Product image of Ibuprofen/Phenylephrin Stada (Phenylephrine Hydrochloride, Ibuprofen) supplied by GNH India

Ibuprofen/Phenylephrin Stada

Active Ingredient:
Phenylephrine Hydrochloride, Ibuprofen
Origin:
EU

Ibuprofen/Phenylephrin Stada (Phenylephrine Hydrochloride, Ibuprofen)

Ibuprofen and phenylephrine hydrochloride, the active ingredients in Ibuprofen/Phenylephrin Stada, are a nonsteroidal anti‑inflammatory drug (NSAID) and an alpha‑adrenergic agonist presented as an oral tablet for oral use. It provides analgesic, antipyretic, anti‑inflammatory and nasal decongestant effects for adults experiencing mild to moderate pain, fever, headache and nasal congestion.

GNH India supplies Ibuprofen/Phenylephrin Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Gmbh

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Indications & Clinical Uses

Ibuprofen/Phenylephrin Stada combines an NSAID and a nasal decongestant to address pain, fever and congestion.

  • Nasal congestion: reduces swelling of nasal mucosa and eases breathing.
  • Headache: alleviates pain through prostaglandin inhibition.
  • Fever: lowers elevated body temperature via anti‑pyretic action.
  • Mild to moderate pain: provides relief from aches such as muscular or dental pain.

How It Works

  • Ibuprofen inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing prostaglandin synthesis and thereby producing analgesic, antipyretic and anti‑inflammatory effects. Phenylephrine hydrochloride selectively stimulates α1‑adrenergic receptors on nasal mucosal blood vessels, causing vasoconstriction that reduces edema and relieves nasal congestion.

Side Effects

Common Side Effects

  • Gastrointestinal discomfort: nausea, heartburn or dyspepsia.
  • Dizziness or mild headache.
  • Nervousness or insomnia.
  • Mild increase in blood pressure.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe allergic reactions such as rash, angioedema or anaphylaxis.
  • Significant hypertension or cardiovascular events.
  • Acute renal impairment, especially in patients with pre‑existing kidney disease.

Precautions & Warnings

Before using Ibuprofen/Phenylephrin Stada, consider the following precautions:

  • Gastrointestinal risk: avoid in patients with active ulcer disease or a history of GI bleeding.
  • Cardiovascular caution: use carefully in individuals with hypertension, heart failure or coronary artery disease.
  • Renal function: monitor kidney function in patients with chronic renal impairment.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Drug interactions: review concomitant medications for potential interactions.
  • Store at ambient temperature (below 25°C): keep in the original pack, protect from moisture.

Avoid Interactions

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Lithium: ibuprofen may raise lithium serum levels.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents (beta‑blockers, ACE inhibitors): phenylephrine may reduce their efficacy.
  • Selective serotonin reuptake inhibitors (SSRIs): may modestly increase bleeding risk.

Frequently Asked Questions

Ibuprofen/Phenylephrin Stada is an over‑the‑counter oral product that combines ibuprofen, an NSAID, with phenylephrine hydrochloride, a nasal decongestant. It is indicated for the temporary relief of mild to moderate pain, fever, headache and nasal congestion associated with the common cold or sinus pressure in adults.

Ibuprofen blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for prostaglandin production. By reducing prostaglandins, it diminishes inflammation, lowers fever, and alleviates pain. Phenylephrine, the second component, activates α1‑adrenergic receptors in the nasal mucosa, causing blood‑vessel constriction and reducing swelling.

The appropriate dose is determined by a qualified prescriber or according to the product label. Dosage depends on factors such as age, weight, severity of symptoms and any concurrent medical conditions. Patients should follow the specific instructions provided by their healthcare professional or the packaging.

Safety data for this combination in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using the product. The prescriber will weigh potential benefits against any possible risks to the mother and infant.

To place an order, visit the product page on gnhindia.com and submit an enquiry with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ibuprofen/Phenylephrin Stada pairs ibuprofen, a widely used NSAID, with phenylephrine, a selective α1‑agonist. Compared with products that contain pseudoephedrine, phenylephrine has a shorter duration of action and a lower risk of central nervous system stimulation, but may be less effective in severe congestion. The ibuprofen component offers stronger anti‑inflammatory and analgesic effects than acetaminophen‑based combos.

Store the tablets at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use it after the expiry date printed on the packaging.

The medication is taken orally with a full glass of water. It may be taken with or without food, although taking it with food can reduce the chance of stomach irritation. Swallow the tablet whole; do not crush, chew, or split it unless directed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, significant hypertension or cardiovascular events, and acute kidney injury, especially in patients with pre‑existing renal disease or who are taking interacting medications.

Individuals with a known hypersensitivity to ibuprofen, phenylephrine, or any other component of the formulation should avoid it. It is also contraindicated in patients with active gastrointestinal ulceration, severe uncontrolled hypertension, recent coronary artery bypass grafting, or severe renal impairment without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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