Product image of Ibuprofen/Phenylephrine Opella (Phenylephrine Hydrochloride, Ibuprofen) supplied by GNH India

Ibuprofen/Phenylephrine Opella

Active Ingredient:
Phenylephrine Hydrochloride, Ibuprofen
Origin:
EU

Ibuprofen/Phenylephrine Opella (Phenylephrine Hydrochloride, Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen/Phenylephrine Opella, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for systemic use. It alleviates headache, fever, minor aches and pains, and, together with phenylephrine, helps reduce nasal congestion associated with colds.

GNH India supplies Ibuprofen/Phenylephrine Opella as a licensed, GDP‑compliant international pharmaceutical supplier, adhering to EU quality standards and providing the product to hospitals, pharmacies and clinics worldwide. The company ensures consistent batch release, proper documentation, and timely delivery across multiple markets.

Manufacturer / TM Owner

Stada Arzneimittel Ag

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Ibuprofen/Phenylephrine Opella combines an NSAID with an alpha‑adrenergic decongestant to address pain‑related and nasal‑congestion conditions.

  • Headache: provides analgesic relief and reduces associated nasal pressure.
  • Fever: lowers elevated body temperature through anti‑pyretic action.
  • Nasal congestion due to common cold or sinusitis: constricts nasal blood vessels to improve airflow.
  • Minor aches and pains: eases muscle or joint discomfort.

How It Works

  • Ibuprofen inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing prostaglandin synthesis and thereby reducing inflammation, pain, and fever. Phenylephrine acts as an alpha‑1 adrenergic receptor agonist, causing vasoconstriction of the nasal mucosa, which diminishes swelling and improves nasal airflow.

Side Effects

Common Side Effects

  • Nausea: mild stomach upset may occur.
  • Dizziness: transient light‑headedness reported.
  • Nasal dryness: due to vasoconstriction.
  • Mild headache: occasional paradoxical headache.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer: severe stomach pain or blood in stool.
  • Anaphylaxis: rapid onset of rash, swelling, and breathing difficulty.
  • Severe hypertension or cardiovascular events: marked rise in blood pressure or chest pain.

Precautions & Warnings

Before using this product, consider the following precautions:

  • Hypersensitivity: avoid if known allergy to ibuprofen, phenylephrine, or other NSAIDs.
  • Peptic ulcer disease: use with caution in patients with active ulcers.
  • Cardiovascular risk: monitor blood pressure in patients with hypertension or heart disease.
  • Anticoagulant therapy: assess bleeding risk when combined with warfarin or similar agents.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Ibuprofen/Phenylephrine Opella may interact with other medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Monoamine oxidase inhibitors (MAOIs): may potentiate hypertensive effects of phenylephrine.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents (beta‑blockers, ACE inhibitors): phenylephrine may reduce their efficacy.
  • Lithium: NSAIDs can raise lithium serum levels.
  • Selective serotonin reuptake inhibitors (SSRIs): modestly increased bleeding risk.

Frequently Asked Questions

Ibuprofen/Phenylephrine Opella is an over‑the‑counter oral combination indicated for the temporary relief of headache, fever, minor aches and pains, and for nasal congestion associated with the common cold or sinusitis.

Ibuprofen blocks cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, reducing prostaglandin production, which lowers inflammation, pain, and fever. Phenylephrine stimulates alpha‑1 receptors, tightening nasal blood vessels to ease congestion.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms, and other medications. Patients should follow the prescriber’s instructions and the product label.

Safety has not been established. Ibuprofen is generally avoided in the third trimester, and phenylephrine is not recommended without medical advice. Pregnant, planning‑pregnant, or breastfeeding women should consult their healthcare provider before use.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with single‑ingredient ibuprofen tablets, this combination adds phenylephrine to address nasal congestion, offering dual symptom relief. Unlike acetaminophen, ibuprofen provides anti‑inflammatory effects but shares similar NSAID cautions. Choice depends on whether congestion is a concurrent symptom.

Store at ambient temperature, preferably below 25 °C, in the original packaging to protect from moisture and light. Keep the product out of reach of children and do not use after the expiry date printed on the pack.

The medication is taken orally, usually with a full glass of water. It may be taken with or without food; taking it with food can reduce stomach irritation. Follow the dosage instructions provided by the prescriber.

Serious risks include gastrointestinal bleeding or ulcer, severe allergic reactions such as anaphylaxis, marked hypertension, and renal impairment. If symptoms like severe stomach pain, vomiting blood, rash, swelling, or breathing difficulty occur, seek medical attention immediately.

People with known hypersensitivity to ibuprofen, phenylephrine, or any NSAID, those with active peptic ulcer disease, uncontrolled hypertension, significant heart failure, or who are taking anticoagulants without medical supervision should avoid this product. Consultation with a healthcare professional is essential.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.