Product image of Ibuprofen Pinewood Laboratories (Ibuprofen) supplied by GNH India

Ibuprofen Pinewood Laboratories

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Pinewood Laboratories (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Pinewood Laboratories, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats pain, fever and inflammation in adults and children when appropriate.
GNH India supplies Ibuprofen Pinewood Laboratories as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pinewood Laboratories Limited

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces inflammation and is indicated for the following conditions:

  • Pain: provides relief from mild to moderate musculoskeletal and dental pain.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammation: diminishes swelling in conditions such as arthritis or soft‑tissue injuries.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis leads to decreased inflammation, analgesia, and antipyresis.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Rash or mild skin irritation.
  • Elevated blood pressure in susceptible individuals.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or perforation.
  • Peptic ulcer disease.
  • Acute renal failure or worsening of chronic kidney disease.
  • Severe hypersensitivity reactions, including anaphylaxis.
  • Hepatotoxicity with marked liver enzyme elevation.
  • Cardiovascular events such as myocardial infarction or stroke, especially with high‑dose or prolonged use.

Precautions & Warnings

Before initiating ibuprofen therapy, consider the following safety measures:

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Evaluate renal function: use caution in those with impaired kidney function.
  • Monitor cardiovascular status: limit use in patients with established heart disease.
  • Use the lowest effective dose for the shortest duration needed.
  • Avoid in individuals with known hypersensitivity to ibuprofen or other NSAIDs.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medication classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration.
  • ACE inhibitors or ARBs: potential reduction in renal perfusion.
  • Lithium: increased lithium serum concentrations.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible reduction in antihypertensive effect.
  • Methotrexate: decreased clearance leading to toxicity.
  • SSRIs: modestly increased bleeding risk.
  • Cyclosporine: enhanced nephrotoxicity.
  • Beta‑blockers: may blunt antihypertensive response.

Frequently Asked Questions

Ibuprofen Pinewood Laboratories is a generic ibuprofen product indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as arthritis, dental procedures, and musculoskeletal injuries. It is commonly prescribed when an NSAID is appropriate for symptom control.

Ibuprofen works by blocking the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins. By reducing prostaglandin synthesis, ibuprofen decreases inflammation, lowers pain signals, and helps bring down elevated body temperature.

The specific dose of ibuprofen is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and response to therapy. Healthcare professionals set the appropriate strength, frequency, and duration for each individual case.

Ibuprofen is generally avoided during the third trimester of pregnancy because of potential fetal cardiovascular effects. During the first two trimesters, it should only be used if clearly needed and prescribed by a healthcare provider. It passes into breast milk in small amounts, so lactating mothers should consult their physician before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details (including any special handling), and assists with import documentation.

Ibuprofen shares a similar mechanism of action with other non‑selective NSAIDs such as naproxen and diclofenac, but it has a relatively shorter half‑life, which may allow for flexible dosing. Its safety profile is comparable, though individual tolerance, gastrointestinal risk, and cardiovascular considerations can differ among agents.

Ibuprofen tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and light, and store out of reach of children. Do not store in damp or excessively hot environments.

Ibuprofen is administered orally, typically as a tablet or capsule that is swallowed whole with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort.

The most serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, acute kidney injury, and increased risk of cardiovascular events like heart attack or stroke, especially with high doses or prolonged therapy. Patients should be monitored for these complications.

Ibuprofen should be avoided in individuals with a known hypersensitivity to ibuprofen or any other NSAID, those with active peptic ulcer disease, severe heart failure, uncontrolled hypertension, or significant renal impairment. It is also contraindicated in the third trimester of pregnancy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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