Ibuprofen Pinewood Laboratories Limited (Ibuprofen)

Ibuprofen works by reversibly inhibiting cyclooxygenase enzymes COX‑1 and COX‑2, which blocks the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis decreases peripheral sensitization of pain receptors, lowers the hypothalamic set‑point for temperature, and limits the inflammatory response in tissues.

The appropriate dose of ibuprofen is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and renal or hepatic function. Dosage may range from low‑dose regimens for fever to higher doses for acute pain, and should always follow the healthcare provider’s instructions.

Ibuprofen is generally avoided in the third trimester of pregnancy because it may affect fetal cardiovascular function and prolong labor. During the first two trimesters, it should be used only if clearly needed and prescribed. It passes into breast milk in small amounts; nursing mothers should consult a physician before use.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any special handling) and assists with import documentation.

Ibuprofen shares the same COX‑inhibiting mechanism as other non‑steroidal anti‑inflammatory drugs such as naproxen or diclofenac, but it has a relatively shorter half‑life, which may require more frequent dosing for sustained effect. Its safety profile is well‑characterized; however, individual risk of gastrointestinal, renal or cardiovascular adverse events may differ among agents, influencing the choice of therapy.

Ibuprofen tablets should be stored at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged or the tablets appear discolored.

Ibuprofen is taken orally, usually with a full glass of water. It can be taken with or without food; however, ingesting it with meals or a snack may lessen gastrointestinal discomfort. The tablet should be swallowed whole and not crushed or chewed unless specifically instructed by a healthcare professional.

The most serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and increased cardiovascular events like myocardial infarction or stroke, especially with high‑dose or prolonged use. Patients should be monitored for signs of bleeding, skin rash, breathing difficulty, or changes in urine output and seek immediate medical attention if these occur.

Ibuprofen should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcer disease, severe heart failure, uncontrolled hypertension, and in the third trimester of pregnancy. Caution is also advised for patients with impaired kidney or liver function, and those taking anticoagulants or certain antihypertensive medications, unless a physician determines that the benefits outweigh the risks.