Product image of Ibuprofen/Pseudoephedrin Haleon (Pseudoephedrine Hydrochloride, Ibuprofen) supplied by GNH India

Ibuprofen/Pseudoephedrin Haleon

Active Ingredient:
Pseudoephedrine Hydrochloride, Ibuprofen
Origin:
EU

Ibuprofen/Pseudoephedrin Haleon (Pseudoephedrine Hydrochloride, Ibuprofen)

Ibuprofen and pseudoephedrine hydrochloride, the active ingredients in Ibuprofen/Pseudoephedrin Haleon, are a non‑steroidal anti‑inflammatory drug (NSAID) and a sympathomimetic nasal decongestant presented as an oral formulation for systemic use. They together relieve pain, fever and nasal congestion in adults.
GNH India supplies Ibuprofen/Pseudoephedrin Haleon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Haleon Germany Gmbh

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Indications & Clinical Uses

  • Ibuprofen/pseudoephedrine combines an NSAID with a nasal decongestant to address pain‑related and congestive conditions.
  • Headache: reduces pain and associated nasal blockage.
  • Fever: lowers elevated body temperature.
  • Musculoskeletal pain: eases inflammation and discomfort in muscles and joints.
  • Sinus pain: relieves sinus pressure and congestion.
  • Nasal congestion: clears nasal passages by vasoconstriction.

How It Works

  • Ibuprofen inhibits cyclo‑oxygenase‑1 and‑2 enzymes, decreasing prostaglandin synthesis and thereby reducing pain, inflammation and fever. Pseudoephedrine hydrochloride stimulates α‑adrenergic receptors on nasal mucosal vessels, causing vasoconstriction and reducing swelling, which eases nasal congestion.

Side Effects

Common Side Effects

  • Nausea or upset stomach
  • Dizziness or light‑headedness
  • Headache
  • Insomnia or difficulty sleeping
  • Dry mouth
  • Mild tremor

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis, swelling of face or throat)
  • High blood pressure or rapid heart rate
  • Significant stomach bleeding or ulceration
  • Hallucinations or severe agitation
  • Skin rash with blistering (Stevens‑Johnson syndrome)
  • Liver or kidney function impairment

Precautions & Warnings

Before using this product, consider the following safety measures.

  • Cardiovascular risk assessment: evaluate blood pressure and heart disease history.
  • Renal function: avoid in severe kidney impairment without medical supervision.
  • Gastro‑intestinal ulcer risk: use cautiously with a history of ulcers or bleeding.
  • Anticoagulant use: monitor closely if combined with blood thinners.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen/pseudoephedrine may interact with several medicines.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis.
  • Other NSAIDs or aspirin: increased gastrointestinal bleeding.
  • Anticoagulants (warfarin, DOACs): heightened bleeding risk.
  • SSRIs or SNRIs: potential for bleeding complications.
  • Antihypertensive agents: may reduce blood‑pressure‑lowering effect.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: possible reduction in decongestant efficacy.
  • Diuretics: may enhance pseudoephedrine‑induced blood‑pressure rise.
  • Lithium: pseudoephedrine can increase lithium levels.
  • Caffeine: additive stimulant effects.
  • Alcohol: increased risk of stomach irritation and dizziness.

Frequently Asked Questions

Ibuprofen/Pseudoephedrin Haleon is indicated for the temporary relief of mild to moderate pain such as headache, musculoskeletal or sinus pain, for reducing fever, and for alleviating nasal congestion associated with colds or allergies. It combines an NSAID with a decongestant to address both pain and congestion in a single oral dose.

Ibuprofen blocks the cyclo‑oxygenase (COX‑1 and COX‑2) enzymes that convert arachidonic acid into prostaglandins, which are mediators of pain, inflammation and fever. By lowering prostaglandin levels, ibuprofen reduces the sensation of pain, diminishes swelling, and helps bring body temperature back to normal.

The exact dose and dosing schedule are determined by the prescribing healthcare professional based on the individual’s age, weight, medical condition and other medications. Patients should follow the prescriber’s instructions and the label directions without exceeding the recommended amount.

Safety in pregnancy and lactation has not been definitively established for this combination. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their doctor before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Compared with single‑ingredient NSAIDs, this combination also provides nasal decongestion, reducing the need for an additional medication. Unlike pure decongestants, it adds analgesic and antipyretic effects. However, the combined profile may increase the risk of cardiovascular or gastrointestinal side effects, so clinicians weigh benefits against potential risks.

Store the product at ambient temperature, preferably below 25 °C (77 °F). Keep it in the original packaging to protect it from moisture and direct sunlight. Do not freeze or expose the tablets to excessive heat.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food, but taking it with food may reduce stomach irritation. Swallow the tablet whole; do not crush or chew unless directed by a healthcare professional.

Serious risks include severe allergic reactions (anaphylaxis), high blood pressure or rapid heart rate, significant gastrointestinal bleeding or ulceration, and rare skin reactions such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms like swelling of the face, difficulty breathing, severe stomach pain, or unexplained bruising.

Individuals with known hypersensitivity to ibuprofen, pseudoephedrine or any component of the formulation should not use it. It is also contraindicated in patients with uncontrolled hypertension, severe heart disease, active gastrointestinal ulceration, or those taking monoamine oxidase inhibitors. Pregnant women and children should only use it under medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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