Product image of Ibuprofen/Pszeudoefedrin (Pseudoephedrine Hydrochloride, Ibuprofen) supplied by GNH India

Ibuprofen/Pszeudoefedrin

Active Ingredient:
Pseudoephedrine Hydrochloride, Ibuprofen
Origin:
EU

Ibuprofen/Pszeudoefedrin (Pseudoephedrine Hydrochloride, Ibuprofen)

Ibuprofen and pseudoephedrine, the active ingredients in Ibuprofen/Pseudoephedrine, are an NSAID and a sympathomimetic decongestant presented as an oral tablet for oral use. They provide analgesic, antipyretic and nasal decongestant effects for adults experiencing pain, fever or nasal congestion.

GNH India supplies Ibuprofen/Pseudoephedrine as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wick Pharma Zweigniederlassung Der Procter & Gamble Gmbh

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Indications & Clinical Uses

Ibuprofen/Pseudoephedrine combines an NSAID with a decongestant to address several common symptoms.

  • Pain relief: reduces mild to moderate pain such as headache, toothache or muscular aches.
  • Fever reduction: lowers elevated body temperature associated with infections or inflammatory conditions.
  • Nasal congestion: eases blocked nasal passages caused by colds, sinusitis or allergic rhinitis.

How It Works

  • Ibuprofen inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing prostaglandin synthesis and thereby producing analgesic, antipyretic and anti‑inflammatory effects. Pseudoephedrine stimulates α‑adrenergic receptors on nasal mucosal blood vessels, causing vasoconstriction that reduces swelling and improves airflow.

Side Effects

The combination may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Nausea: mild stomach upset or queasiness.
  • Headache: transient head discomfort.
  • Dizziness: feeling light‑headed or unsteady.
  • Dry mouth: reduced salivation.
  • Insomnia: difficulty falling or staying asleep.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Gastrointestinal bleeding: black stools or vomiting blood.
  • Hypertension: significant increase in blood pressure.
  • Tachycardia: rapid heart rate.
  • Anaphylaxis: severe, life‑threatening allergic response.

Precautions & Warnings

Before using Ibuprofen/Pseudoephedrine, consider the following safety measures.

  • Assess renal function: ibuprofen can affect kidney performance.
  • Avoid in uncontrolled hypertension: pseudoephedrine may raise blood pressure.
  • Use with caution in asthma: sympathomimetic effects can trigger bronchospasm.
  • Do not combine with other NSAIDs: increases risk of gastrointestinal injury.
  • Limit alcohol intake: may enhance stomach irritation.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen/Pseudoephedrine may interact with several drug classes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • SSRIs (e.g., sertraline): heightened bleeding tendency.
  • MAO inhibitors: potential hypertensive crisis with pseudoephedrine.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may diminish decongestant effectiveness.
  • ACE inhibitors: possible reduction in antihypertensive effect.

Frequently Asked Questions

Ibuprofen/Pseudoephedrine is used to relieve mild to moderate pain, lower fever, and reduce nasal congestion caused by colds, sinusitis or allergic rhinitis. It combines an analgesic/antipyretic NSAID with a sympathomimetic decongestant to address these symptoms in a single oral tablet.

Ibuprofen blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the production of prostaglandins—chemicals that cause pain, fever and inflammation. By lowering prostaglandin levels, ibuprofen provides analgesic and antipyretic effects.

The appropriate dose is determined by a prescriber based on the patient’s age, weight, medical history and the severity of symptoms. Healthcare professionals will select the strength and frequency that best matches the individual’s therapeutic needs.

Safety information for pregnancy and lactation is limited. Healthcare providers usually weigh the potential benefits against possible risks before prescribing. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the product with their doctor before use.

To place an order, visit the product page on gnhindia.com, enter the required quantity and submit the enquiry form. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The combined tablet offers convenience by delivering both agents in a single dose, which can improve adherence. Pharmacologically, the effects are similar to taking each drug individually, but the fixed‑dose combination may limit flexibility in adjusting the amount of each component.

Store the tablets at room temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and light, and place them out of reach of children.

The medication is taken orally with a full glass of water. It can be taken with or without food, although taking it with food may reduce stomach irritation. Follow the prescriber’s instructions regarding timing and frequency.

Serious risks include gastrointestinal bleeding, severe allergic reactions such as anaphylaxis, significant increases in blood pressure, and rapid heart rate. Patients should seek immediate medical attention if they experience symptoms like vomiting blood, severe stomach pain, rash with swelling, or chest discomfort.

Individuals with known hypersensitivity to ibuprofen, pseudoephedrine or any component of the tablet should avoid it. It is also contraindicated in patients with uncontrolled hypertension, severe coronary artery disease, certain arrhythmias, or those taking monoamine oxidase inhibitors. A healthcare professional should evaluate suitability before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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