Product image of Ibuprofen Puren (Ibuprofen) supplied by GNH India

Ibuprofen Puren

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Puren (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Puren, is a nonsteroidal anti‑inflammatory drug presented as an oral dosage form for oral use. It reduces pain, fever and inflammation in adults and children when appropriate.

GNH India supplies Ibuprofen Puren as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Customers benefit from consistent batch consistency, regulatory compliance, and responsive technical support throughout the procurement process.

Manufacturer / TM Owner

Puren Pharma Gmbh & Co. Kg

1
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Indications & Clinical Uses

Ibuprofen is an NSAID that alleviates pain and inflammation across several musculoskeletal and febrile conditions.

  • Mild to moderate pain: provides analgesia for headaches, dental pain, menstrual cramps and musculoskeletal aches.
  • Fever: reduces elevated body temperature associated with infections or inflammatory states.
  • Osteoarthritis: helps relieve joint pain and improve function in degenerative joint disease.
  • Rheumatoid arthritis: reduces joint inflammation and pain in autoimmune arthritis.
  • Inflammation: diminishes localized swelling in soft‑tissue injuries.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which catalyze the conversion of arachidonic acid to prostaglandins. By decreasing prostaglandin synthesis, it reduces peripheral sensitization of nociceptors, lowers the hypothalamic set‑point for temperature, and limits inflammatory exudate formation, thereby providing analgesic, antipyretic and anti‑inflammatory actions.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild and transient to serious and potentially life‑threatening.

Common Side Effects

  • Nausea: mild gastrointestinal upset that may resolve with food.
  • Headache: transient mild to moderate head discomfort.
  • Rash: mild skin erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe allergic reactions such as anaphylaxis or angioedema.
  • Renal impairment: acute kidney injury or reduced renal function.

Precautions & Warnings

When using ibuprofen, several precautionary measures should be observed to minimize risk.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding before initiating therapy.
  • Evaluate renal function: monitor creatinine in patients with existing kidney disease.
  • Monitor cardiovascular status: use lowest effective dose in individuals with heart disease or hypertension.
  • Avoid concurrent NSAIDs: do not combine with other non‑steroidal anti‑inflammatory drugs.
  • Check for hypersensitivity: discontinue if signs of allergic reaction appear.
  • Store at ambient temperature: keep in original container, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • Diuretics: may enhance renal adverse effects.
  • Methotrexate: reduced clearance leading to toxicity.
  • SSRIs: increased bleeding tendency.

Frequently Asked Questions

Ibuprofen Puren is used to relieve mild to moderate pain such as headaches, dental pain, menstrual cramps and musculoskeletal aches, to reduce fever, and to treat inflammation associated with conditions like osteoarthritis, rheumatoid arthritis and soft‑tissue injuries.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the production of prostaglandins. Lower prostaglandin levels diminish pain signaling, lower fever by acting on the hypothalamus, and decrease inflammation in affected tissues.

The appropriate dose of Ibuprofen Puren is determined by a qualified prescriber based on the individual’s age, weight, medical condition and response to therapy. Patients should follow the dosing instructions provided by their healthcare professional.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and clinical circumstances. It is generally avoided in the third trimester and used only if clearly needed in earlier stages. Breastfeeding mothers should consult a healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen shares the same class mechanism as other non‑steroidal anti‑inflammatory drugs, offering comparable analgesic, antipyretic and anti‑inflammatory effects. Compared with some NSAIDs, ibuprofen has a relatively short half‑life, which may influence dosing frequency and risk profile for gastrointestinal or cardiovascular events.

Ibuprofen Puren should be stored at ambient temperature, below 25 °C, in its original packaging. The container should be kept tightly closed, protected from moisture, direct sunlight and excessive heat to maintain product stability.

Ibuprofen Puren is taken orally, usually with a glass of water. It may be taken with or without food, although taking it with food can help reduce gastrointestinal discomfort. The exact administration schedule should follow the prescriber’s instructions.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, and acute kidney injury, especially in patients with pre‑existing renal impairment or when used with interacting medications.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant renal or hepatic disease should avoid using Ibuprofen Puren unless specifically directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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