Product image of Ibuprofen Schmerztabletten Interpharm Gmbh (Ibuprofen) supplied by GNH India

Ibuprofen Schmerztabletten Interpharm Gmbh

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Schmerztabletten Interpharm Gmbh (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Schmerztabletten Interpharm Gmbh, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a tablet for oral use. It treats pain, fever and inflammation in adults and children as appropriate.

GNH India supplies Ibuprofen Schmerztabletten Interpharm Gmbh as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Interpharm Gmbh

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces pain, fever and inflammation by inhibiting prostaglandin synthesis.

  • Pain: provides relief of mild to moderate acute or chronic pain such as headache, dental or musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory conditions.
  • Inflammation: diminishes swelling and tenderness in conditions like arthritis or soft‑tissue injury.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin levels lead to decreased inflammation, lower pain signaling, and diminished fever response in the hypothalamus.

Side Effects

Common Side Effects

  • Stomach upset or dyspepsia.
  • Nausea.
  • Dizziness.
  • Headache.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe allergic reaction (anaphylaxis).
  • Acute kidney injury or impaired renal function.

Precautions & Warnings

Before using ibuprofen tablets, consider the following precautions:

  • Assess medical history: verify presence of ulcers, kidney disease, cardiovascular disorders, asthma, or pregnancy.
  • Use the lowest effective dose: limit duration to the shortest period needed for symptom control.
  • Avoid concomitant NSAIDs: concurrent use increases gastrointestinal and renal risk.
  • Monitor renal function: especially in elderly, dehydrated, or patients on diuretics.
  • Store at ambient temperature: keep below 25°C, in the original pack, and protect from moisture.

Avoid Interactions

Ibuprofen may interact with several medicines. Review the list before co‑administration.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: increased ulceration potential.
  • Selective serotonin reuptake inhibitors (SSRIs): amplified bleeding tendency.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible reduction in renal perfusion.
  • Lithium: ibuprofen can raise lithium serum levels.
  • Methotrexate: decreased clearance may lead to toxicity.
  • Antihypertensives: may blunt blood‑pressure‑lowering effect.
  • Oral hypoglycemics: potential alteration of glucose control.

Frequently Asked Questions

Ibuprofen Schmerztabletten Interpharm Gmbh contains ibuprofen, an NSAID indicated for the temporary relief of mild to moderate pain, reduction of fever, and alleviation of inflammation associated with conditions such as headache, dental pain, musculoskeletal injuries, and arthritic disorders.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. Lower prostaglandin levels reduce inflammation, diminish pain‑signal transmission, and reset the hypothalamic set‑point for body temperature, thereby relieving pain, swelling, and fever.

The appropriate dose of ibuprofen tablets is determined by the prescribing healthcare professional based on the individual’s age, weight, clinical condition, and response to therapy. Dosage may vary from low‑strength tablets for mild symptoms to higher strengths for more severe pain, always following the prescriber’s instructions.

Ibuprofen is generally avoided during the third trimester of pregnancy because of potential fetal cardiovascular effects. Use during the first two trimesters should only occur if clearly needed and prescribed. While small amounts pass into breast milk, it is usually considered compatible with breastfeeding when used at the lowest effective dose, but a clinician’s guidance is essential.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details (including any temperature requirements), and assists with import documentation.

Both ibuprofen and naproxen are non‑selective NSAIDs that inhibit COX enzymes, but naproxen has a longer half‑life, allowing twice‑daily dosing, whereas ibuprofen often requires more frequent dosing. Naproxen may have a slightly lower cardiovascular risk profile, while ibuprofen is associated with a quicker onset of analgesia. Choice depends on clinical needs, dosing convenience, and individual risk factors.

Ibuprofen tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original container to protect from moisture and light, and ensure the packaging is tightly closed. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Ibuprofen tablets are taken orally with a full glass of water. They may be swallowed with or without food; taking them with food or milk can reduce gastrointestinal discomfort. The tablet should be swallowed whole and not chewed, crushed, or dissolved unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe allergic reactions such as anaphylaxis, and acute kidney injury, especially in patients with pre‑existing renal impairment or dehydration. Cardiovascular events like heart attack or stroke may also be increased with high‑dose or long‑term use. Prompt medical attention is required if any of these symptoms arise.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, active peptic ulcer disease, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment should avoid ibuprofen. It is also contraindicated in the third trimester of pregnancy and in patients taking certain anticoagulants without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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