Product image of Ibuprofen Seven Plus Pain Relief Aspire Pharma (Ibuprofen) supplied by GNH India

Ibuprofen Seven Plus Pain Relief Aspire Pharma

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Seven Plus Pain Relief Aspire Pharma (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Seven Plus Pain Relief Aspire Pharma, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is employed to relieve mild to moderate pain, reduce fever, and diminish inflammation in adults and children as appropriate.

GNH India supplies Ibuprofen Seven Plus Pain Relief Aspire Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance across multiple regions.

Manufacturer / TM Owner

Aspire Pharma Limited

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Indications & Clinical Uses

  • Ibuprofen, an NSAID, reduces prostaglandin‑mediated inflammation and is indicated for the following conditions:
  • Pain: Provides symptomatic relief of mild to moderate nociceptive pain such as headache, dental pain, and musculoskeletal aches.
  • Fever: Lowers elevated body temperature associated with infectious or inflammatory processes.
  • Inflammation: Decreases swelling and discomfort in conditions like arthritis or soft‑tissue injury.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2. This blockade reduces the conversion of arachidonic acid to prostaglandins and thromboxanes, mediators that promote pain, fever, and inflammation. By lowering prostaglandin synthesis at sites of tissue injury, ibuprofen diminishes peripheral sensitisation of nociceptors and the febrile response, resulting in analgesic, antipyretic, and anti‑inflammatory actions.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort, nausea, or dyspepsia.
  • Headache or dizziness.
  • Mild skin rash or itching.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Renal impairment or acute kidney injury.
  • Severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome.
  • Cardiovascular events including thrombotic complications.
  • Hepatotoxicity or blood dyscrasias.

Precautions & Warnings

  • When using ibuprofen, several safety considerations should be observed:
  • Assess renal function: evaluate kidney health before initiating therapy, especially in patients with dehydration or chronic kidney disease.
  • Monitor gastrointestinal risk: use the lowest effective dose and consider gastro‑protective agents in patients with a history of ulcer disease.
  • Avoid in known hypersensitivity: discontinue if rash, angioedema, or anaphylaxis occurs.
  • Caution with concomitant anticoagulants: increased bleeding risk requires close monitoring.
  • Store at ambient temperature: keep below 25 °C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness of the interaction level helps manage risk.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • High‑dose aspirin: competitive inhibition increasing toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion; monitor kidney function.
  • Diuretics (loop or thiazide): risk of renal impairment; monitor electrolytes.
  • Lithium: ibuprofen can increase lithium levels; monitor serum concentrations.

Frequently Asked Questions

Ibuprofen Seven Plus Pain Relief Aspire Pharma contains ibuprofen, an NSAID that is used to relieve mild to moderate pain, lower fever, and reduce inflammation. It is commonly prescribed for headaches, dental pain, musculoskeletal aches, febrile illnesses, and inflammatory conditions such as arthritis.

Ibuprofen works by reversibly inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2. This reduces the synthesis of prostaglandins, which are chemicals that mediate pain, fever, and inflammation. Lower prostaglandin levels lead to decreased sensitisation of pain receptors and a reduced febrile response.

The appropriate dose of ibuprofen is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and any relevant medical history. Dosage recommendations may differ for pain, fever, or inflammatory indications, and the prescriber will tailor the regimen accordingly.

Ibuprofen is generally avoided during the third trimester of pregnancy because it may affect fetal cardiovascular function. Use during earlier pregnancy or while breastfeeding should only occur if the prescriber judges the benefit outweighs potential risks. Always discuss with a healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. The sales team then replies with pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

The most common alternative to ibuprofen is acetaminophen, which provides analgesic and antipyretic effects but lacks anti‑inflammatory activity. Compared with other NSAIDs, ibuprofen has a relatively short half‑life and a well‑established safety profile, though all NSAIDs share risks of gastrointestinal irritation and renal effects.

Ibuprofen oral tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and direct sunlight. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Ibuprofen is taken by mouth, usually with a full glass of water. It can be taken with or without food; taking it with food or milk may reduce gastrointestinal discomfort. Swallow tablets whole; do not crush or chew unless a specific formulation advises otherwise.

Serious risks include gastrointestinal ulceration or bleeding, especially in patients with a history of ulcer disease; renal impairment, which may present as reduced urine output or swelling; cardiovascular events such as heart attack or stroke in high‑risk individuals; and severe allergic reactions like anaphylaxis or Stevens‑Johnson syndrome.

Ibuprofen should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients with severe renal or hepatic impairment, and in the third trimester of pregnancy. Caution is also advised for patients on anticoagulants, certain antihypertensives, or with uncontrolled hypertension.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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