Product image of Ibuprofen Siromed (Ibuprofen) supplied by GNH India

Ibuprofen Siromed

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Siromed (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Siromed, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an oral formulation for systemic use. It relieves mild to moderate pain, reduces fever, and eases inflammatory conditions such as arthritis in adults and children when appropriate.
GNH India supplies Ibuprofen Siromed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Uab Nvt

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Indications & Clinical Uses

Ibuprofen acts systemically to reduce inflammation and pain associated with several common conditions.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal aches, and postoperative discomfort.
  • Fever: lowers elevated body temperature by acting on the hypothalamic heat‑regulation center.
  • Inflammatory conditions such as arthritis: decreases joint swelling, stiffness, and pain by inhibiting prostaglandin synthesis.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin levels diminishes inflammation, pain signaling, and fever generation throughout the body.

Side Effects

Adverse reactions may occur with ibuprofen use and are categorized by frequency and severity.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache or dizziness.
  • Mild skin rash or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Acute renal impairment, especially in volume‑depleted patients.
  • Severe hypersensitivity reactions, including anaphylaxis or Stevens‑Johnson syndrome.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding disorders.
  • Monitor renal function: especially in patients with chronic kidney disease or dehydration.
  • Avoid in known hypersensitivity: discontinue immediately if allergic signs appear.
  • Use the lowest effective dose: limit duration to the shortest period necessary for symptom control.
  • Avoid concomitant anticoagulants: increased risk of bleeding when combined with warfarin or similar agents.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Concurrent use with anticoagulants (e.g., warfarin): heightened risk of serious bleeding.
  • Combination with other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Use with selective serotonin reuptake inhibitors (SSRIs): increased hemorrhagic potential.

Moderate Interactions (Monitor Closely)

  • Concomitant ACE inhibitors or diuretics: may reduce renal perfusion and function.
  • Co‑administration with lithium: possible elevation of lithium serum levels.
  • Use with methotrexate: ibuprofen can raise methotrexate concentrations, raising toxicity risk.

Frequently Asked Questions

Ibuprofen Siromed is used to relieve mild to moderate pain, lower fever, and reduce inflammation associated with conditions such as arthritis, dental pain, musculoskeletal aches, and postoperative discomfort. It belongs to the NSAID class and works systemically after oral administration.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin production, it diminishes pain signaling, reduces inflammation, and helps reset the body’s temperature set‑point to lower fever.

The appropriate dose of Ibuprofen Siromed is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and response to therapy. Healthcare professionals tailor the dosage and frequency to achieve optimal symptom control while minimizing risk.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester because of potential fetal complications, and caution is advised during early pregnancy and while breastfeeding. Patients should always consult their healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs), and required import documentation.

Ibuprofen offers a balanced profile of analgesic, antipyretic, and anti‑inflammatory effects with a relatively short half‑life, allowing flexible dosing. Compared with naproxen, it has a quicker onset but may require more frequent dosing. Unlike acetaminophen, ibuprofen also reduces inflammation but carries a higher gastrointestinal risk.

Ibuprofen Siromed should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight, and excessive heat. Do not use if the packaging is damaged or the tablets appear discolored.

Ibuprofen Siromed is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food or milk may reduce gastrointestinal discomfort. Swallow tablets whole; do not crush or chew unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, and acute kidney injury, especially in patients with pre‑existing renal impairment or dehydration. Prompt medical attention is required if any of these symptoms develop.

Ibuprofen Siromed should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration or bleeding, severe heart failure, and in the third trimester of pregnancy. Patients with significant renal or hepatic disease should consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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