Product image of Ibuprofen Stada (Ibuprofen Sodium) supplied by GNH India

Ibuprofen Stada

Active Ingredient:
Ibuprofen Sodium
Origin:
EU

Ibuprofen Stada (Ibuprofen Sodium)

Ibuprofen, the active ingredient in Ibuprofen Stada, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a suppository for rectal use. It treats mild to moderate pain, fever, inflammatory conditions and dysmenorrhea in adults and children as appropriate.

GNH India supplies Ibuprofen Stada as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stadapharm Gmbh

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Indications & Clinical Uses

  • Ibuprofen Stada, an NSAID, provides analgesic, antipyretic and anti‑inflammatory effects by reducing prostaglandin synthesis.
  • Mild to moderate pain: alleviates discomfort from musculoskeletal, dental or postoperative sources.
  • Fever: lowers elevated body temperature in febrile states.
  • Inflammatory conditions (e.g., arthritis, dysmenorrhea): decreases swelling and pain related to inflammation.

How It Works

  • Ibuprofen sodium reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting reduction in prostaglandin levels diminishes inflammation, pain signalling and the hypothalamic set‑point for body temperature, producing analgesic, antipyretic and anti‑inflammatory actions.

Side Effects

Ibuprofen Stada may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Skin reactions: mild rash or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration: potentially life‑threatening hemorrhage.
  • Renal impairment: acute kidney injury, especially with dehydration.
  • Severe hypersensitivity: anaphylaxis, angioedema.
  • Hepatotoxicity: elevated liver enzymes or hepatitis.

Precautions & Warnings

  • Before using Ibuprofen Stada, consider the following precautions.
  • Assess renal function: avoid use in patients with severe kidney disease.
  • Monitor gastrointestinal risk: use with caution in history of ulcers or bleeding.
  • Avoid in late pregnancy: NSAIDs may affect fetal circulation.
  • Use lowest effective dose: limit duration to the shortest necessary.
  • Check for drug interactions: review concomitant anticoagulants, antihypertensives, other NSAIDs.
  • Store at room temperature: keep in original packaging, protect from moisture and heat.

Avoid Interactions

Ibuprofen Stada can interact with several medicines; review them with a healthcare professional.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding potential.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function.
  • Diuretics: risk of renal impairment and electrolyte imbalance.
  • Lithium: NSAIDs can increase lithium levels.

Frequently Asked Questions

Ibuprofen Stada is a rectal suppository containing ibuprofen sodium. It is indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammatory conditions such as arthritis or dysmenorrhea. The formulation allows systemic absorption when oral administration is not feasible.

Ibuprofen works by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the synthesis of prostaglandins, which are mediators of pain, fever, and inflammation. Lower prostaglandin levels result in analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Ibuprofen Stada is determined by the prescribing clinician based on the patient’s age, weight, condition, and response. The prescriber will select the strength and frequency that best balances efficacy with safety, following local prescribing guidelines.

Ibuprofen, like other NSAIDs, should be used with caution during pregnancy, especially in the third trimester, because it may affect fetal circulation and renal function. Breastfeeding mothers should consult a healthcare professional, as ibuprofen can be excreted in milk in small amounts.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ibuprofen Stada offers a rectal route, which can be advantageous when oral intake is impossible or when rapid systemic absorption is desired. Compared with naproxen, ibuprofen has a shorter half‑life, allowing quicker onset but may require more frequent dosing. Efficacy and safety profiles are broadly similar across NSAIDs when used at recommended doses.

Store Ibuprofen Stada at room temperature, below 25 °C, in its original packaging. Protect the suppositories from moisture, direct sunlight and excessive heat to maintain stability. Keep out of reach of children and do not use if the packaging is damaged.

The suppository is inserted rectally, preferably after a bowel movement. The patient should lie on the left side with the right knee drawn toward the chest, gently push the suppository past the anal sphincter using a gloved finger or applicator, and remain lying down for a few minutes to ensure absorption.

Serious risks include gastrointestinal bleeding or ulceration, severe renal impairment, hypersensitivity reactions such as anaphylaxis, and hepatotoxicity. Patients should be monitored for signs of bleeding, sudden loss of kidney function, rash, or liver dysfunction, and seek immediate medical attention if these occur.

Ibuprofen Stada should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, severe renal or hepatic impairment, and in the third trimester of pregnancy. Caution is also advised for patients on anticoagulants or with uncontrolled hypertension.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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