Product image of Ibuprofen The Boots Company (Ibuprofen) supplied by GNH India

Ibuprofen The Boots Company

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen The Boots Company (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen The Boots Company, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for oral use. It is used to relieve pain, reduce fever, and lessen inflammation in adults and children when appropriate.

GNH India supplies Ibuprofen The Boots Company as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

The Boots Company Plc

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Indications & Clinical Uses

Ibuprofen acts as an NSAID to manage symptoms associated with inflammatory and febrile conditions.

  • Pain: provides analgesia for mild to moderate musculoskeletal, dental and headache pain.
  • Fever: lowers elevated body temperature in febrile illnesses.
  • Inflammation: reduces swelling and discomfort in conditions such as arthritis or minor injuries.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis diminishes inflammation, pain signaling, and the hypothalamic set‑point for temperature regulation.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin irritation or erythema.
  • Elevated blood pressure: modest increase in some patients.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reactions: anaphylaxis, angioedema.
  • Hepatic injury: elevated liver enzymes or hepatitis.
  • Renal impairment: acute kidney injury or worsening chronic kidney disease.
  • Cardiovascular events: myocardial infarction or stroke, particularly with high‑dose or prolonged use.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Cardiovascular risk: avoid high‑dose or long‑term use in patients with heart disease.
  • Gastrointestinal history: use cautiously in individuals with ulcers or bleeding disorders.
  • Renal function: monitor kidney function in patients with existing renal impairment.
  • Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Ibuprofen can affect the activity of several other medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: additive renal and cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive effect.
  • Diuretics: may diminish diuretic efficacy and affect kidney function.
  • Lithium: ibuprofen can raise serum lithium levels, requiring monitoring.

Frequently Asked Questions

Ibuprofen The Boots Company is used to relieve mild to moderate pain, lower fever, and reduce inflammation associated with conditions such as musculoskeletal aches, dental pain, headaches, arthritis, and febrile illnesses. It provides symptomatic relief by targeting the underlying inflammatory pathways.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, it diminishes pain signals, reduces swelling, and helps reset the body’s temperature set‑point during fever.

The specific dose of ibuprofen is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. Patients should follow the prescriber’s instructions and the product labeling for appropriate dosing.

Safety of ibuprofen during pregnancy or lactation depends on the trimester and individual health factors. It is generally avoided in the third trimester because of potential fetal cardiovascular effects. Breastfeeding mothers should consult a healthcare provider before use to assess risks and benefits.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ibuprofen shares a similar mechanism with other non‑selective NSAIDs such as naproxen and diclofenac, but it often has a shorter half‑life and may be preferred for short‑term pain or fever. Compared with selective COX‑2 inhibitors, ibuprofen carries a lower risk of cardiovascular events but a higher risk of gastrointestinal irritation.

Ibuprofen tablets should be stored at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keeping the product in a dry place helps maintain its potency and stability throughout its shelf life.

Ibuprofen is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort. The tablet should be swallowed whole and not chewed or crushed unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and increased cardiovascular events like heart attack or stroke, especially with high doses or prolonged therapy. Patients should seek immediate medical attention if they experience signs of these conditions.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or advanced kidney disease should avoid ibuprofen. Pregnant women in the third trimester and patients on anticoagulant therapy should also consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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