Ibuprofen The Mentholatum Company (Ibuprofen)

When applied to the skin, ibuprofen penetrates the superficial layers and inhibits cyclooxygenase enzymes (COX‑1 and COX‑2) in peripheral tissues. This reduces the synthesis of prostaglandins, which are mediators of pain, swelling, and inflammation, thereby delivering localized relief at the site of application.

The appropriate amount of topical ibuprofen is determined by the prescribing healthcare professional based on the specific condition, treatment area, and patient factors. Patients should follow the prescriber’s instructions regarding the quantity of gel or cream to apply and the frequency of use.

Safety of topical ibuprofen in pregnancy or lactation has not been definitively established. Healthcare providers generally advise caution and may recommend alternative treatments, especially during the first trimester or while breastfeeding, to avoid potential risks to the fetus or infant.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Topical ibuprofen delivers the active ingredient directly to the skin, offering localized pain relief with lower systemic exposure compared with oral ibuprofen. This can reduce the likelihood of gastrointestinal side effects, but the overall analgesic effect may be limited to the area of application.

Store the product at room temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture, direct sunlight and excessive heat. Ensure the container is tightly closed to maintain product stability.

Apply a thin layer of the gel or cream to clean, dry skin over the affected area. Gently massage until fully absorbed, unless otherwise directed by a healthcare professional. Do not cover the treated area with airtight dressings unless instructed.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, toxic epidermal necrolysis, and systemic NSAID toxicity if large amounts are absorbed. Immediate medical attention is required if signs of a severe reaction appear.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with open wounds, infected or inflamed skin at the application site, and patients taking anticoagulant therapy should avoid using this product unless advised otherwise by a clinician.