Product image of Ibuprofen Trekpleister (Ibuprofen) supplied by GNH India

Ibuprofen Trekpleister

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofen Trekpleister (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofen Trekpleister, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It provides analgesic, antipyretic, and anti‑inflammatory effects for the relief of mild to moderate pain, fever, and inflammatory conditions in adults and children when appropriate.

GNH India supplies Ibuprofen Trekpleister as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies worldwide. The company follows stringent quality standards and provides reliable sourcing for healthcare providers across global markets. Its distribution network ensures timely delivery and compliance with local regulatory requirements.

Manufacturer / TM Owner

Mae Holding Bv

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Indications & Clinical Uses

Ibuprofen Trekpleister, an NSAID, acts on the prostaglandin pathway to provide relief in several common conditions.

  • Pain (headache, dental, musculoskeletal): Reduces pain intensity by decreasing inflammation and sensitization of nociceptors, offering relief for mild to moderate acute pain.
  • Fever: Lowers elevated body temperature by inhibiting prostaglandin synthesis in the hypothalamus, providing antipyretic effect.
  • Inflammatory conditions (e.g., arthritis, sprains): Diminishes swelling and discomfort by suppressing inflammatory mediators in affected tissues.

How It Works

  • Ibuprofen inhibits cyclooxygenase enzymes COX‑1 and COX‑2, which catalyze the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it decreases inflammation, pain signaling, and fever generation. The reversible inhibition allows temporary suppression of these pathways without permanently altering enzyme structure. The drug’s effect on COX‑1 also reduces thromboxane A2 production, modestly influencing platelet aggregation, while COX‑2 inhibition primarily accounts for its anti‑inflammatory and antipyretic actions.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort or dyspepsia.
  • Nausea or mild vomiting.
  • Headache.
  • Dizziness.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reactions such as rash, angioedema, or anaphylaxis.
  • Acute renal impairment, especially in dehydrated patients.
  • Hepatic injury presenting as elevated liver enzymes or jaundice.

Precautions & Warnings

Before using Ibuprofen Trekpleister, consider the following precautions.

  • Assess renal function: avoid use in severe renal impairment.
  • Monitor gastrointestinal risk: use with food or consider gastroprotection in high‑risk patients.
  • Avoid in known hypersensitivity to ibuprofen or other NSAIDs.
  • Use cautiously in cardiovascular disease: may increase risk of thrombotic events.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with other medicines; review the following categories.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • High‑dose aspirin: enhanced renal toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function.
  • Diuretics: potential for reduced efficacy and renal effects.
  • Lithium: increased serum lithium levels.

Frequently Asked Questions

Ibuprofen Trekpleister is an over‑the‑counter NSAID used to relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, and arthritic disorders.

Ibuprofen works by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for converting arachidonic acid into prostaglandins. Lower prostaglandin levels decrease pain signaling, lower fever, and reduce inflammatory swelling.

The appropriate dose of Ibuprofen Trekpleister is determined by a qualified prescriber or pharmacist based on the individual’s age, weight, condition being treated, and any relevant medical history. Patients should follow the specific instructions provided with the product.

Ibuprofen is generally avoided during the third trimester of pregnancy because it may affect fetal cardiovascular function. During early pregnancy and while breastfeeding, use only if the prescriber determines that the benefits outweigh potential risks. Consultation with a healthcare professional is essential.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with acetaminophen, ibuprofen provides both analgesic and anti‑inflammatory effects, making it useful for conditions involving swelling. However, ibuprofen carries a higher risk of gastrointestinal and renal side effects, whereas acetaminophen is generally gentler on the stomach but lacks anti‑inflammatory activity.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and direct sunlight. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Ibuprofen Trekpleister is taken orally with a full glass of water. It can be taken with or without food, although taking it with food may reduce the likelihood of stomach upset. Swallow the tablet whole; do not crush or chew unless instructed otherwise.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, acute kidney injury especially in dehydrated individuals, and rare liver toxicity. Patients experiencing black stools, severe rash, swelling of the face, or sudden loss of kidney function should seek immediate medical attention.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe renal or hepatic impairment, and patients in the third trimester of pregnancy should avoid using Ibuprofen Trekpleister unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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