Product image of Ibuprofene Aristo Pharma (Ibuprofen) supplied by GNH India

Ibuprofene Aristo Pharma

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofene Aristo Pharma (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofene Aristo Pharma, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve pain, reduce fever, and decrease inflammation in adults and children when appropriate. The medication works by targeting the biochemical pathways that generate discomfort and swelling, making it a common choice for conditions such as headache, dental pain, musculoskeletal aches, and febrile episodes.

GNH India supplies Ibuprofene Aristo Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aristo Pharma Gmbh (Art 57)

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Indications & Clinical Uses

Ibuprofen acts on the cyclooxygenase pathway to provide analgesic, antipyretic and anti‑inflammatory effects.

  • Pain: Alleviates mild to moderate acute pain such as headache, toothache, menstrual cramps, or musculoskeletal discomfort.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory conditions.
  • Inflammation: Reduces swelling and stiffness in soft tissues caused by injury or overuse.
  • Arthritis: Improves joint pain and functional limitation in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen reversibly inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, preventing the conversion of arachidonic acid into prostaglandins. This reduction in prostaglandin synthesis diminishes nociceptor sensitization, lowers the hypothalamic set‑point for temperature, and curtails vascular permeability and leukocyte infiltration that drive inflammation.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Cardiovascular events: increased risk of heart attack or stroke, especially with high‑dose or prolonged use.

Precautions & Warnings

When considering ibuprofen therapy, several safety measures should be observed.

  • Assess renal function: avoid use in patients with severe kidney disease or dehydration.
  • Evaluate gastrointestinal risk: use caution in individuals with a history of ulcers or bleeding.
  • Monitor cardiovascular status: limit use in patients with uncontrolled hypertension or heart disease.
  • Review concomitant medications: avoid concurrent use with other NSAIDs, anticoagulants, or corticosteroids without medical supervision.
  • Store at ambient temperature: keep below 25 °C in the original container, protected from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs) or other serotonergic agents: heightened bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce antihypertensive effect and impair renal function.
  • Diuretics: potential for decreased kidney perfusion and electrolyte imbalance.
  • Lithium: ibuprofen can raise lithium serum levels, risking toxicity.

Frequently Asked Questions

Ibuprofene Aristo Pharma contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, lower fever, and reduce inflammation. It is indicated for conditions such as headache, dental pain, musculoskeletal aches, fever associated with infections, and inflammatory joint disorders like osteoarthritis and rheumatoid arthritis.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are key steps in the production of prostaglandins. By lowering prostaglandin levels, it reduces the sensitisation of pain receptors, lowers the hypothalamic set‑point for body temperature, and diminishes the inflammatory response in tissues.

The appropriate dose of ibuprofen is determined by the prescribing healthcare professional based on the patient’s age, weight, the severity of symptoms, and any relevant medical conditions. Dosage recommendations can differ between over‑the‑counter and prescription formulations, and the prescriber will tailor the regimen to each individual.

Ibuprofen is generally avoided during the third trimester of pregnancy because it may affect fetal cardiovascular development. Use during the first two trimesters should only occur if clearly needed and prescribed by a physician. While small amounts pass into breast milk, most guidelines advise caution and recommend consulting a healthcare provider before using ibuprofen while nursing.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Ibuprofene Aristo Pharma. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details, and any necessary import documentation.

The most common alternative to ibuprofen is acetaminophen (paracetamol), which provides analgesic and antipyretic effects but lacks significant anti‑inflammatory activity. Ibuprofen, as an NSAID, also reduces inflammation and may be more effective for musculoskeletal pain, but it carries a higher risk of gastrointestinal and renal side effects compared with acetaminophen.

Ibuprofene Aristo Pharma should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

Ibuprofen is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food or milk may reduce the likelihood of stomach upset. The tablet or capsule should be swallowed whole and not chewed or crushed unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, especially in patients with a history of ulcers or who use anticoagulants. Renal impairment can occur, particularly in dehydrated individuals or those with pre‑existing kidney disease. Cardiovascular events such as heart attack or stroke may be heightened with high‑dose or long‑term use, and severe skin reactions like Stevens‑Johnson syndrome are rare but critical to recognize.

Ibuprofen should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients with severe renal or hepatic impairment, and persons with uncontrolled hypertension or certain cardiovascular conditions. It is also contraindicated in the third trimester of pregnancy and should be used with caution in the first two trimesters after medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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