Product image of Ibuprofene Arrow Lab (Ibuprofen) supplied by GNH India

Ibuprofene Arrow Lab

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofene Arrow Lab (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofene Arrow Lab, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It provides analgesic, antipyretic and anti-inflammatory effects for the relief of mild to moderate pain, fever and inflammatory conditions in adults and children when prescribed.

GNH India supplies Ibuprofene Arrow Lab as a licensed, GDP‑compliant international pharmaceutical product to hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory conformity across markets.

Manufacturer / TM Owner

Arrow Generiques

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Indications & Clinical Uses

Ibuprofen acts on inflammatory pathways to relieve symptoms associated with pain, fever and inflammation.

  • Pain: Reduces mild to moderate pain such as headache, dental pain, menstrual cramps.
  • Fever: Lowers elevated body temperature associated with infections or other febrile conditions.
  • Inflammation: Decreases swelling and stiffness in conditions like osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis diminishes peripheral sensitisation of nociceptors, lowers the hypothalamic set‑point for temperature, and limits inflammatory exudate formation, thereby producing analgesic, antipyretic and anti‑inflammatory actions.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate headache.
  • Dizziness: transient light‑headedness.
  • Rash: mild skin irritation or itching.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding: serious GI complications.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Hepatotoxicity: elevated liver enzymes or hepatitis.
  • Severe hypersensitivity: anaphylaxis or angioedema.

Precautions & Warnings

Before using ibuprofen, consider the following precautions.

  • Assess renal function: evaluate kidney health before initiating therapy, especially in patients with dehydration or chronic kidney disease.
  • Monitor gastrointestinal risk: use the lowest effective dose and consider gastro‑protective agents in patients with a history of ulcers.
  • Check cardiovascular status: use cautiously in patients with hypertension, heart failure or coronary artery disease.
  • Avoid use in late pregnancy: ibuprofen is contraindicated in the third trimester due to fetal risks.
  • Store at ambient temperature: keep below 25 °C, in original packaging, protected from moisture and light.

Avoid Interactions

Ibuprofen can interact with several medicines; some require avoidance while others need close monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened ulcer risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Lithium: increased serum lithium concentrations.

Frequently Asked Questions

Ibuprofene Arrow Lab contains ibuprofen, an NSAID that is used to relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as headaches, dental pain, musculoskeletal disorders, and febrile illnesses. It is prescribed for adults and, when appropriate, for children under medical supervision.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, ibuprofen reduces the sensitisation of pain receptors, lowers the hypothalamic set‑point for body temperature, and diminishes the inflammatory response.

The appropriate dose of Ibuprofene Arrow Lab is set by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Dosage may differ for pain, fever, or inflammatory disorders, and the prescriber will consider any relevant medical history before recommending a regimen.

Ibuprofen is generally avoided in the third trimester of pregnancy because it may affect fetal cardiovascular development. Use during the first two trimesters should only occur if the potential benefit outweighs the risk and under medical advice. Limited data exist for breastfeeding, so a clinician should evaluate safety before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Ibuprofene Arrow Lab. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofen and naproxen belong to the same NSAID class and share similar mechanisms of COX inhibition. Ibuprofen has a shorter half‑life, often requiring multiple daily doses, whereas naproxen provides longer‑lasting relief with fewer doses. Both carry comparable gastrointestinal and cardiovascular risks, but individual tolerance and specific clinical scenarios guide the choice.

Ibuprofene Arrow Lab should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture, light and excessive heat, and ensure they are out of reach of children.

The product is intended for oral administration. Tablets are swallowed whole with a full glass of water, preferably with food or milk to minimise gastrointestinal irritation. The exact dosing schedule and duration are determined by the prescribing clinician.

Serious adverse events include gastrointestinal bleeding or ulceration, severe renal impairment, hepatotoxicity, and hypersensitivity reactions such as anaphylaxis. Cardiovascular risks, such as increased blood pressure or thrombotic events, may also occur, especially with high‑dose or prolonged therapy.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulceration or bleeding, severe renal or hepatic impairment, and patients in the third trimester of pregnancy should avoid this medication. Caution is also advised for patients with uncontrolled hypertension or significant cardiovascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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