Product image of Ibuprofene B. Braun Melsungen (Ibuprofen) supplied by GNH India

Ibuprofene B. Braun Melsungen

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofene B. Braun Melsungen (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofene B. Braun Melsungen, is a nonsteroidal anti-inflammatory drug presented as an intravenous injection for intravenous use. It is employed to relieve pain, reduce fever, and control inflammation, including postoperative discomfort, in hospital patients.

GNH India supplies Ibuprofene B. Braun Melsungen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Ibuprofene B. Braun Melsungen, an NSAID, acts on inflammatory pathways to provide symptomatic relief in several clinical situations.

  • Pain: reduces acute and postoperative pain severity.
  • Fever: lowers elevated body temperature associated with infection or inflammation.
  • Inflammation: diminishes swelling and tissue inflammation in surgical and musculoskeletal contexts.
  • Postoperative pain: provides rapid analgesia after surgical procedures.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis limits inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions may occur with any intravenous NSAID. Most are mild and transient, but serious events are possible.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Headache: transient cranial discomfort.
  • Dizziness: occasional light‑headedness.
  • Injection site pain: local discomfort at the infusion site.
  • Elevated blood pressure: modest rise in systolic/diastolic values.
  • Renal function changes: slight increase in serum creatinine.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: severe ulceration or hemorrhage.
  • Anaphylaxis: acute allergic reaction with airway compromise.
  • Hepatotoxicity: elevated liver enzymes or liver injury.
  • Severe renal impairment: acute kidney injury.
  • Cardiovascular events: myocardial infarction or stroke.
  • Thrombocytopenia: reduced platelet count leading to bleeding.

Precautions & Warnings

Before using Ibuprofene B. Braun Melsungen, consider the following safety measures.

  • Assess renal function: avoid in patients with severe kidney disease.
  • Monitor hepatic status: use cautiously in liver impairment.
  • Evaluate cardiovascular risk: limit use in patients with recent myocardial infarction or uncontrolled hypertension.
  • Check for hypersensitivity: do not administer to individuals with known NSAID allergy.
  • Avoid concurrent anticoagulants: increased bleeding risk when combined with warfarin or similar agents.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Ibuprofene B. Braun Melsungen may interact with several drug classes, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • High‑dose aspirin: additive gastrointestinal toxicity.
  • ACE inhibitors or ARBs: potential reduction in renal perfusion.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible decrease in antihypertensive effect.
  • Lithium: increased lithium serum concentrations.
  • Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Ibuprofene B. Braun Melsungen is an intravenous formulation of ibuprofen used in hospital settings to manage acute pain, reduce fever, and control inflammation, including postoperative pain. It provides rapid systemic exposure, making it suitable for patients who cannot take oral medications.

The ibuprofen in this product reversibly blocks cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, the drug diminishes pain signaling, reduces fever, and limits inflammatory swelling.

The specific dose and infusion rate are determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and renal or hepatic function. Healthcare professionals follow local guidelines and product labeling to set the appropriate regimen.

The safety of intravenous ibuprofen in pregnancy has not been definitively established, and it is generally avoided in the third trimester due to potential fetal risks. Breastfeeding mothers should consult their physician, as ibuprofen can be excreted in milk in small amounts.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Intravenous ibuprofen delivers the drug directly into the bloodstream, achieving faster and more predictable plasma concentrations than oral formulations. This route is advantageous for patients unable to swallow tablets or when rapid analgesia is required, while oral ibuprofen remains convenient for outpatient use.

Ibuprofene B. Braun Melsungen must be stored at 2‑8 °C, protected from light, and should never be frozen or shaken. Before administration, inspect the vial for particulate matter and ensure the solution is at room temperature if required by the clinical protocol.

The product is given as an intravenous infusion. The healthcare professional selects an appropriate infusion set, dilutes the drug if required by the label, and administers it over the recommended time period, monitoring the patient for any adverse reactions.

Serious risks include gastrointestinal bleeding, severe allergic reactions such as anaphylaxis, acute kidney injury, hepatotoxicity, and cardiovascular events like myocardial infarction or stroke. Prompt recognition and management of these events are essential.

Patients with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulceration, severe renal or hepatic impairment, uncontrolled hypertension, or recent major cardiovascular events should avoid this medication unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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