Product image of Ibuprofene Eg (Ibuprofen) supplied by GNH India

Ibuprofene Eg

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofene Eg (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofene Eg, is a nonsteroidal anti-inflammatory drug presented as an oral dosage form for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects for the relief of mild to moderate pain, fever and inflammatory conditions such as arthritis in adults.

GNH India supplies Ibuprofene Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution for this essential NSAID today.

Manufacturer / TM Owner

Eg S.P.A.

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Indications & Clinical Uses

  • Ibuprofen acts on inflammatory pathways to relieve pain and fever.
  • Mild to moderate pain: provides analgesic relief by inhibiting prostaglandin synthesis, thereby reducing pain perception in conditions such as headache, toothache, menstrual cramps and musculoskeletal aches.
  • Fever: lowers elevated body temperature through antipyretic action by acting on the hypothalamic heat‑regulation center, useful in febrile illnesses.
  • Arthritis and other inflammatory conditions: diminishes inflammation, swelling and associated discomfort in osteoarthritis, rheumatoid arthritis and other musculoskeletal inflammatory disorders.

How It Works

  • Ibuprofen exerts its effect by non‑selectively and reversibly inhibiting cyclo‑oxygenase enzymes COX‑1 and COX‑2, which blocks the conversion of arachidonic acid to prostaglandins and thromboxanes. This reduction in prostaglandin synthesis decreases inflammation, pain signalling and fever generation at peripheral tissues and the hypothalamus, while also modestly affecting platelet aggregation.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash: mild erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe allergic reactions: anaphylaxis, angioedema.
  • Hepatotoxicity or renal impairment.

Precautions & Warnings

When using ibuprofen, consider the following precautions to minimize risk.

  • Assess cardiovascular risk: use the lowest effective dose and avoid long‑term therapy in patients with heart disease.
  • Evaluate gastrointestinal history: avoid in individuals with active ulcers or a history of bleeding.
  • Monitor renal function: caution in patients with impaired kidney function or dehydration.
  • Use cautiously in asthma: may trigger bronchospasm in aspirin‑sensitive individuals.
  • Avoid use during the third trimester of pregnancy: potential fetal complications.
  • Store at ambient temperature: keep in original packaging, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness of major and moderate interactions helps ensure safe use.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • High‑dose aspirin: additive gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: heightened cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce antihypertensive effect and impair renal function.
  • Diuretics: potential for reduced kidney perfusion.
  • Lithium: ibuprofen may increase lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Ibuprofene Eg contains ibuprofen, an NSAID indicated for relief of mild to moderate pain, reduction of fever, and management of inflammatory conditions such as arthritis. It is commonly prescribed for headaches, dental pain, musculoskeletal aches, and febrile illnesses in adults, providing analgesic, antipyretic and anti‑inflammatory effects.

Ibuprofen works by non‑selectively inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin production, it reduces inflammation, pain signaling, and the hypothalamic response that raises body temperature, resulting in analgesic, antipyretic, and anti‑inflammatory actions.

The appropriate dose of Ibuprofene Eg is determined by the prescribing healthcare professional based on the patient’s condition, age, weight and response. Dosage may vary from single low‑dose tablets for occasional pain to higher or multiple doses for more severe inflammation, always following the prescriber’s instructions and local labeling.

Ibuprofen is generally avoided during the third trimester of pregnancy because it may affect fetal cardiovascular development and reduce amniotic fluid. In earlier trimesters, use should be limited and only under medical advice. While small amounts are excreted in breast milk, nursing mothers should consult a healthcare provider before using ibuprofen.

To request Ibuprofene Eg, visit the product page on gnhindia.com, submit an enquiry with the desired quantity, and provide institutional or trade credentials. GNH India’s procurement team will verify the information, then respond with pricing, availability, shipping details (including any required temperature control) and assistance with import documentation.

Ibuprofene Eg shares the same mechanism as other non‑selective NSAIDs such as naproxen and diclofenac, offering comparable analgesic and anti‑inflammatory efficacy. Differences lie in pharmacokinetic profiles, dosing frequency and individual tolerability; ibuprofen typically has a shorter half‑life, allowing flexible dosing but may require more frequent administration for sustained effect.

Ibuprofene Eg should be stored at ambient temperature, preferably below 25 °C, in its original container to protect it from moisture, light and excessive heat. Keeping the product in a dry place helps maintain its stability and potency throughout its shelf life.

Ibuprofene Eg is taken orally, usually with a full glass of water. It may be taken with or without food; however, ingesting it with meals can reduce the likelihood of gastrointestinal discomfort. Patients should follow the dosing schedule prescribed by their healthcare professional.

The most serious adverse effects of ibuprofen include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and renal impairment, especially in patients with pre‑existing kidney disease or dehydration. Cardiovascular events, such as heart attack or stroke, may also be heightened with prolonged high‑dose use.

Ibuprofen is contraindicated in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration, severe heart failure, or during the third trimester of pregnancy. Patients with uncontrolled hypertension, significant renal or hepatic impairment should also avoid ibuprofen unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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