Product image of Ibuprofeno Alter (Ibuprofen) supplied by GNH India

Ibuprofeno Alter

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Alter (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Alter, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammation, including arthritic conditions, in adult patients.

GNH India supplies Ibuprofeno Alter as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Alter, S.A.

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Indications & Clinical Uses

Ibuprofeno Alter, an NSAID, works on the prostaglandin pathway to relieve several common conditions.

  • Pain: Reduces mild to moderate pain such as headache, dental pain, or musculoskeletal discomfort.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammation: Decreases swelling and redness in soft tissues, including minor injuries.
  • Arthritis: Alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it diminishes inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions to ibuprofen can range from mild to severe, depending on individual susceptibility and dosage.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache or dizziness.
  • Mild skin rash or itching.
  • Elevated blood pressure in some patients.
  • Transient increase in serum creatinine.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or perforation.
  • Peptic ulcer disease.
  • Acute renal failure or worsening of chronic kidney disease.
  • Severe allergic reactions, including anaphylaxis.
  • Hepatotoxicity with elevated liver enzymes.
  • Rare dermatologic conditions such as Stevens‑Johnson syndrome.

Precautions & Warnings

Before using Ibuprofeno Alter, consider the following safety measures.

  • Renal function assessment: evaluate kidney health, especially in the elderly or dehydrated.
  • Cardiovascular risk: use the lowest effective dose in patients with heart disease or hypertension.
  • Hypersensitivity: avoid if a known allergy to ibuprofen or other NSAIDs exists.
  • Concomitant alcohol: limit alcohol intake to reduce gastrointestinal bleeding risk.
  • Dose limitation: adhere to the prescriber's recommended amount and duration.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofeno Alter can affect the activity of several other medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Corticosteroids: additive risk of ulceration and bleeding.
  • Lithium: ibuprofen may raise lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function.
  • Diuretics: may impair renal perfusion when combined.
  • Selective serotonin reuptake inhibitors (SSRIs): modest increase in bleeding risk.
  • Beta‑blockers: potential attenuation of blood‑pressure control.
  • Antihypertensive agents: monitor blood pressure for additive effects.

Frequently Asked Questions

Ibuprofeno Alter contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, lower fever, and reduce inflammation. It is indicated for headaches, dental pain, musculoskeletal aches, fever associated with infections, and inflammatory conditions such as osteoarthritis and rheumatoid arthritis.

Ibuprofen works by blocking the cyclooxygenase (COX‑1 and COX‑2) enzymes, which are required to convert arachidonic acid into prostaglandins. Prostaglandins mediate pain, fever, and inflammation, so their reduction leads to decreased symptom intensity and improved comfort.

The appropriate dose of Ibuprofeno Alter is determined by a qualified prescriber based on the patient’s age, weight, medical condition, and response to therapy. Patients should follow the healthcare professional’s instructions and never exceed the recommended amount.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because it may affect fetal circulation. Women who are pregnant or nursing should discuss alternatives with their obstetrician or physician before using this product.

To place an order, visit the product page on gnhindia.com, enter the required quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ibuprofeno Alter offers the same active ingredient as other ibuprofen products, providing a well‑studied balance of analgesic, antipyretic, and anti‑inflammatory effects. Compared with stronger NSAIDs such as diclofenac or naproxen, ibuprofen generally has a shorter half‑life and a lower risk of certain cardiovascular events, but individual response and safety profiles vary.

Store Ibuprofeno Alter at temperatures below 25 °C in a dry place. Keep the tablets in their original container, protect them from moisture, heat, and direct sunlight, and keep them out of reach of children.

Ibuprofeno Alter is taken orally with a full glass of water. It may be taken with or without food; however, taking it with food can reduce the likelihood of stomach irritation. Swallow the tablet whole; do not crush or chew unless specifically directed by a healthcare professional.

The most serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and acute kidney injury, especially in patients with pre‑existing renal disease or dehydration. Patients should seek immediate medical attention if they notice black stools, severe abdominal pain, swelling, or signs of an allergic reaction.

Individuals with a known hypersensitivity to ibuprofen or any NSAID, those with active gastrointestinal bleeding or ulcer disease, patients with severe heart failure, and persons in the third trimester of pregnancy should avoid using Ibuprofeno Alter. Consultation with a healthcare provider is essential for anyone with chronic medical conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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