Product image of Ibuprofeno Ambah (Ibuprofen) supplied by GNH India

Ibuprofeno Ambah

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Ambah (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Ambah, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an intravenous injection for intravenous use. It is indicated for the management of mild to moderate pain, reduction of fever, and control of inflammatory conditions, particularly in postoperative or acute care settings.

GNH India supplies Ibuprofeno Ambah as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing EU‑sourced, prescription‑only medication to meet global healthcare needs.

Manufacturer / TM Owner

Ambah Limited

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Indications & Clinical Uses

Ibuprofen injection is used to address pain, fever and inflammation through systemic cyclooxygenase inhibition.

  • Post‑operative pain: provides analgesia to reduce discomfort after surgery.
  • Acute mild to moderate pain: alleviates pain from injuries or procedures.
  • Fever: lowers elevated body temperature in febrile patients.
  • Inflammatory conditions: reduces inflammation in conditions such as musculoskeletal injuries.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes peripheral sensitization, lowers the fever set‑point in the hypothalamus, and decreases inflammatory exudate formation, resulting in analgesic, antipyretic and anti‑inflammatory actions.

Side Effects

Intravenous ibuprofen may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Dyspepsia: discomfort or burning in the stomach.
  • Headache: transient head pain.
  • Injection site reactions: erythema or pain at the infusion site.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: severe hemorrhage in the GI tract.
  • Renal impairment: acute kidney injury or reduced renal function.
  • Anaphylaxis: severe allergic reaction with respiratory compromise.
  • Hepatotoxicity: liver enzyme elevations or injury.

Precautions & Warnings

When using Ibuprofeno Ambah, clinicians should observe several safety measures.

  • Assess renal function: evaluate baseline kidney status before use.
  • Monitor blood pressure: watch for hypertension during therapy.
  • Use with caution in patients with peptic ulcer disease: risk of GI complications.
  • Avoid in patients with known hypersensitivity to ibuprofen or other NSAIDs.
  • Limit duration: use the lowest effective dose for the shortest period necessary.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Ibuprofeno Ambah can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive GI and renal toxicity.
  • Corticosteroids: heightened risk of gastrointestinal ulceration.
  • ACE inhibitors or ARBs: may reduce renal perfusion leading to kidney injury.

Moderate Interactions (Monitor Closely)

  • Diuretics: potential for reduced antihypertensive effect.
  • Lithium: ibuprofen may increase lithium serum levels.
  • Methotrexate (high dose): decreased clearance and toxicity risk.

Frequently Asked Questions

Ibuprofeno Ambah is an intravenous formulation of ibuprofen, a non‑steroidal anti‑inflammatory drug. It is prescribed by healthcare professionals to manage mild to moderate pain, reduce fever, and control acute inflammatory conditions, especially in postoperative or hospital settings where rapid systemic effect is required.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are key in the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin production, it diminishes peripheral sensitization, reduces the hypothalamic fever set‑point, and limits inflammatory mediators, producing analgesic, antipyretic, and anti‑inflammatory effects.

The specific dose and infusion rate of Ibuprofeno Ambah are determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and renal function. Healthcare providers follow local guidelines and product labeling to select an appropriate dosage regimen for each individual case.

Safety data for intravenous ibuprofen in pregnancy and lactation are limited, and the product is generally classified as contraindicated or to be used only if the potential benefit outweighs the risk. Clinicians should evaluate maternal and fetal considerations and consider alternative therapies when safer options are available.

To request Ibuprofeno Ambah, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details—including any cold‑chain requirements—and necessary import documentation.

Compared with other injectable NSAIDs such as ketorolac or diclofenac, ibuprofen offers a broader therapeutic window for pain, fever and inflammation with a well‑characterized safety profile. It provides comparable analgesia but may have a lower risk of renal toxicity at standard doses, though individual patient factors and drug‑specific contraindications must guide selection.

Ibuprofeno Ambah must be stored refrigerated at 2 °C to 8 °C. The vials should be kept in their original packaging, protected from light, and must not be frozen or shaken. If the product reaches room temperature, it should be used promptly and not re‑refrigerated.

The medication is supplied as a sterile solution for intravenous injection. It is administered by a qualified healthcare professional, typically as a slow infusion over 15–30 minutes, depending on the prescribed dose and patient tolerance. Proper aseptic technique and infusion set compatibility are essential to ensure safe delivery.

The most serious adverse reactions include gastrointestinal bleeding, acute renal impairment, severe allergic reactions such as anaphylaxis, and hepatotoxicity. Patients with a history of ulcers, kidney disease, or hypersensitivity to NSAIDs should be closely monitored, and any signs of bleeding, sudden loss of kidney function, or allergic symptoms require immediate medical attention.

Ibuprofeno Ambah is contraindicated in patients with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration, severe renal or hepatic impairment, and in those receiving anticoagulant therapy where bleeding risk is unacceptable. It should also be avoided in individuals with a history of asthma exacerbated by NSAIDs unless the prescriber determines that benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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