Product image of Ibuprofeno Aurovitas (Ibuprofen) supplied by GNH India

Ibuprofeno Aurovitas

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Aurovitas (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Aurovitas, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects, helping to relieve mild to moderate pain, reduce fever, and diminish swelling associated with musculoskeletal and arthritic conditions in both adult and pediatric patients when appropriate.

GNH India supplies Ibuprofeno Aurovitas as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across global markets.

Manufacturer / TM Owner

Aurovitas Spain,s.A.U.

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Indications & Clinical Uses

  • Ibuprofen acts as an analgesic, antipyretic and anti‑inflammatory agent, addressing conditions that involve pain, fever and inflammation.
  • Pain: Provides relief from mild to moderate pain such as headache, dental pain, menstrual cramps or musculoskeletal discomfort.
  • Fever: Reduces elevated body temperature associated with infections or inflammatory processes.
  • Inflammation: Decreases swelling and redness in conditions like sprains, strains or soft‑tissue injuries.
  • Arthritic conditions: Alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting the cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which catalyze the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin synthesis, it reduces the sensitisation of nociceptors, lowers the hypothalamic set‑point for temperature, and diminishes vascular permeability and inflammatory cell recruitment.

Side Effects

Ibuprofen may cause a range of adverse reactions, from mild and frequent to rare but serious.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Rash or mild skin irritation.
  • Elevated liver enzymes (asymptomatic).

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe allergic reactions such as anaphylaxis or angioedema.
  • Acute kidney injury or reduced renal function.
  • Hepatotoxicity with jaundice.
  • Cardiovascular events such as myocardial infarction or stroke.

Precautions & Warnings

  • Before using Ibuprofeno Aurovitas, consider the following precautions to minimise risk.
  • Assess gastrointestinal risk: evaluate history of ulcers, bleeding or chronic NSAID use.
  • Monitor renal function: avoid in patients with severe kidney impairment or dehydration.
  • Use cautiously in cardiovascular disease: consider increased risk of thrombotic events.
  • Review concomitant medications: avoid combining with other NSAIDs, anticoagulants or corticosteroids without medical guidance.
  • Pregnancy and lactation: discuss with a healthcare professional before use.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging and protect from moisture.

Avoid Interactions

Ibuprofen can interact with several medicines; some combinations should be avoided while others require close monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Corticosteroids: amplified risk of ulceration and bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs): enhanced bleeding tendency.
  • ACE inhibitors or ARBs in patients with renal insufficiency: may reduce renal function.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible reduction in antihypertensive effect.
  • Lithium: ibuprofen may raise lithium serum levels.
  • Methotrexate: decreased clearance leading to toxicity.
  • Oral hypoglycemics: potential alteration of blood glucose control.
  • Antihypertensive agents: may blunt blood pressure‑lowering response.

Frequently Asked Questions

Ibuprofeno Aurovitas contains ibuprofen, an NSAID that is indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation. It is commonly used in conditions such as headache, dental pain, musculoskeletal aches, febrile illnesses, and inflammatory disorders including osteoarthritis and rheumatoid arthritis.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 (COX‑1/COX‑2) enzymes. This inhibition blocks the conversion of arachidonic acid to prostaglandins, which are mediators of pain, fever, and inflammation. Lower prostaglandin levels reduce nociceptor sensitisation, lower hypothalamic temperature set‑point, and diminish inflammatory swelling.

The appropriate dose of Ibuprofeno Aurovitas is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Dosage regimens may vary, and patients should follow the specific instructions provided by their prescriber or pharmacist.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester because of potential fetal cardiovascular effects, and caution is advised earlier in pregnancy. Breastfeeding mothers should consult a healthcare provider, as ibuprofen does pass into breast milk in small amounts.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Ibuprofeno Aurovitas. GNH India works with hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofeno Aurovitas offers a familiar NSAID profile similar to other ibuprofen‑based products, providing effective analgesic, antipyretic and anti‑inflammatory actions with a relatively short half‑life. Compared with agents such as naproxen or diclofenac, ibuprofen generally has a quicker onset but may require more frequent dosing. Choice among NSAIDs depends on individual patient tolerance, comorbidities and physician preference.

Store Ibuprofeno Aurovitas at ambient temperature, preferably below 25 °C (77 °F). Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Ibuprofeno Aurovitas is taken orally, usually with a full glass of water. It can be taken with food or milk to lessen gastrointestinal discomfort, although it may also be taken on an empty stomach if tolerated. Patients should swallow the tablet whole and not crush or chew it unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal ulceration or bleeding, especially in patients with a history of ulcers or who use anticoagulants. Renal impairment can occur, particularly in dehydrated individuals or those with pre‑existing kidney disease. Cardiovascular events such as myocardial infarction or stroke may be heightened with long‑term use, and severe allergic reactions like anaphylaxis are possible but rare.

Ibuprofeno Aurovitas should be avoided in individuals with known hypersensitivity to ibuprofen or any other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, severe renal or hepatic impairment, and patients in the third trimester of pregnancy. Caution is also advised for patients with uncontrolled hypertension, heart failure, or a history of cardiovascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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