Product image of Ibuprofeno B. Braun (Ibuprofen) supplied by GNH India

Ibuprofeno B. Braun

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno B. Braun (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno B. Braun, is a nonsteroidal anti-inflammatory drug presented as an injectable solution for intravenous use. It treats pain, fever and inflammation in hospital settings.

GNH India supplies Ibuprofeno B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

  • Ibuprofen is an NSAID that reduces pain, fever and inflammation by inhibiting prostaglandin synthesis.
  • Pain: Provides analgesic relief for acute and chronic painful conditions.
  • Fever: Lowers elevated body temperature in adults and children.
  • Inflammation: Decreases swelling associated with musculoskeletal and postoperative inflammation.
  • Post‑operative pain: Controls moderate to severe pain after surgical procedures.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, blocking the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes peripheral sensitisation of nociceptors, lowers the hypothalamic set‑point for temperature, and limits inflammatory exudate formation, resulting in analgesic, antipyretic and anti‑inflammatory effects.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Nausea or vomiting
  • Dyspepsia or abdominal discomfort
  • Headache
  • Dizziness
  • Injection‑site pain or erythema
  • Transient rise in blood pressure

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Acute renal impairment or failure
  • Severe hypersensitivity reactions, including anaphylaxis
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Thrombocytopenia or other hematologic abnormalities
  • Hepatotoxicity with elevated liver enzymes

Precautions & Warnings

  • Before initiating therapy, clinicians should evaluate patient‑specific risk factors and monitor for potential complications.
  • Renal function: Assess baseline kidney function and adjust use in patients with chronic renal disease.
  • Cardiovascular risk: Use cautiously in individuals with hypertension or heart failure.
  • Bleeding tendency: Avoid in patients with active peptic ulcer disease or coagulopathy.
  • Pregnancy category D: Limit use to situations where benefits outweigh risks, especially after the first trimester.
  • Drug interactions: Review concomitant medications for additive NSAID effects.
  • Store at ambient temperature: Keep in original container, protect from light and moisture.

Avoid Interactions

Ibuprofeno B. Braun may alter the pharmacodynamics or pharmacokinetics of several co‑administered agents.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • SSRIs or SNRIs: heightened bleeding potential.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion, especially in volume‑depleted patients.
  • Diuretics: potential for reduced renal clearance of ibuprofen.
  • Lithium: ibuprofen can raise serum lithium concentrations, requiring level monitoring.

Frequently Asked Questions

Ibuprofeno B. Braun is an intravenous formulation of ibuprofen used in hospital settings to provide analgesic, antipyretic and anti‑inflammatory effects. It is commonly employed for the management of moderate to severe pain, fever, and inflammation, including postoperative pain after surgical procedures.

The ibuprofen in Ibuprofeno B. Braun reversibly blocks COX‑1 and COX‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish peripheral nociceptor sensitisation, lower the hypothalamic temperature set‑point, and limit inflammatory mediators, producing pain relief, fever reduction, and decreased swelling.

The specific dose and infusion rate of Ibuprofeno B. Braun are determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and response to therapy. Healthcare professionals should follow institutional protocols and the product’s prescribing information when selecting the appropriate regimen.

Ibuprofeno B. Braun is classified as pregnancy category D, indicating potential risk to the fetus, especially after the first trimester. Use is reserved for situations where the therapeutic benefit justifies the risk. Limited data are available for breastfeeding; clinicians should weigh potential infant exposure against maternal benefit.

To request Ibuprofeno B. Braun, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Compared with oral NSAIDs, the intravenous route of Ibuprofeno B. Braun offers rapid onset of action and predictable plasma concentrations, which can be advantageous in acute pain or when oral administration is not feasible. Its safety profile is similar to other ibuprofen products, but the IV formulation avoids gastrointestinal irritation associated with oral dosing.

Ibuprofeno B. Braun should be stored at ambient temperature, protected from light and moisture, and kept in its original packaging until use. Do not freeze the solution. Inspect the vial for particulate matter or discoloration before administration, and discard any product that appears compromised.

The product is supplied as a sterile injectable solution for intravenous infusion. It is administered by a healthcare professional using aseptic technique, typically diluted in compatible IV fluids and infused over a period dictated by the prescribed dose and patient tolerance. Monitoring during infusion is recommended.

Serious adverse events include gastrointestinal bleeding or ulceration, acute renal failure, severe hypersensitivity reactions such as anaphylaxis, and rare hematologic or hepatic complications. Patients with a history of ulcer disease, renal impairment, or bleeding disorders should be closely monitored, and therapy should be discontinued if serious reactions occur.

Ibuprofeno B. Braun is contraindicated in patients with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal bleeding or ulceration, severe uncontrolled heart failure, and in the third trimester of pregnancy. Caution is also advised for individuals with significant renal, hepatic or cardiovascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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