Product image of Ibuprofeno Braun (Ibuprofen) supplied by GNH India

Ibuprofeno Braun

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Braun (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Braun, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as a intravenous solution for intravenous use. It treats mild to moderate pain, fever, inflammation, postoperative pain and musculoskeletal pain in adults.

GNH India supplies Ibuprofeno Braun as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

B.Braun Medical, S.A.

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Indications & Clinical Uses

Ibuprofeno Braun is an NSAID that reduces inflammation and pain through cyclooxygenase inhibition.

  • Mild to moderate pain: provides analgesia for acute and chronic pain conditions.
  • Fever: lowers elevated body temperature associated with infection or inflammation.
  • Inflammation: diminishes swelling in musculoskeletal and postoperative settings.
  • Post‑operative pain: manages pain after surgical procedures.
  • Musculoskeletal pain: alleviates discomfort from strains, sprains, and arthritis.

How It Works

  • Ibuprofen reversibly inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis leads to lowered inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Dyspepsia: indigestion or stomach discomfort.
  • Headache: transient cranial pain.
  • Dizziness: occasional light‑headedness.
  • Injection site reactions: redness or mild swelling.
  • Transient renal function changes: slight increase in serum creatinine.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe renal failure or acute kidney injury.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Anaphylactic or severe allergic reactions.
  • Hepatic necrosis or severe liver injury.
  • Cardiovascular thrombotic events (rare).

Precautions & Warnings

Before initiating therapy, clinicians should evaluate patient‑specific risk factors.

  • Assess renal function: check baseline kidney parameters.
  • Monitor gastrointestinal risk: avoid in patients with active ulcers or bleeding disorders.
  • Avoid concomitant anticoagulants: increased bleeding potential.
  • Use with caution in asthma: may provoke bronchospasm.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Ibuprofeno Braun can alter the effect of several co‑administered medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • Corticosteroids: increased ulceration potential.
  • SSRIs or SNRIs: amplified bleeding tendency.
  • ACE inhibitors in compromised renal function: risk of acute kidney injury.

Moderate Interactions (Monitor Closely)

  • Diuretics: may reduce renal perfusion.
  • Lithium: potential increase in serum lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.
  • Cyclosporine: enhanced nephrotoxic effect.
  • Beta‑blockers: possible masking of tachycardia.

Frequently Asked Questions

Ibuprofeno Braun is an intravenous formulation of ibuprofen used in hospital settings to manage mild to moderate pain, reduce fever, and control inflammation associated with conditions such as postoperative recovery, musculoskeletal injuries, and acute febrile states.

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, it diminishes pain signaling, reduces fever, and limits inflammatory swelling at the site of tissue injury.

The specific dose and infusion rate of Ibuprofeno Braun are determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and response to therapy. Healthcare professionals should follow local guidelines and product labeling.

Safety data for intravenous ibuprofen in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Ibuprofeno Braun offers rapid systemic exposure via intravenous delivery, which can be advantageous in acute care when oral administration is not feasible. Compared with oral NSAIDs, it provides more predictable plasma concentrations but shares a similar safety profile regarding gastrointestinal, renal, and cardiovascular risks.

Ibuprofeno Braun must be stored at 2‑8 °C in a refrigerator. Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking the solution. Do not use if the product appears discolored or contains particles.

The medication is given as an intravenous infusion by a qualified healthcare professional. The infusion rate and total dose are calculated by the prescriber and administered through a suitable IV line, following aseptic technique and standard infusion protocols.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe renal impairment, hypersensitivity reactions such as anaphylaxis, and rare but life‑threatening skin reactions like Stevens‑Johnson syndrome. Patients should be monitored closely for signs of these events.

Ibuprofeno Braun is contraindicated in patients with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal bleeding or ulcer disease, severe renal or hepatic impairment, and in those who have experienced previous severe allergic reactions to similar agents.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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