Product image of Ibuprofeno Cinfamed (Ibuprofen) supplied by GNH India

Ibuprofeno Cinfamed

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Cinfamed (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Cinfamed, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for systemic use. It is used to relieve mild to moderate pain, reduce fever, and diminish inflammation in adults and children when appropriate.

GNH India supplies Ibuprofeno Cinfamed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards, manufactures under EU regulations, and provides reliable global distribution after rigorous testing to ensure consistency and safety.

Manufacturer / TM Owner

Laboratorios Cinfa S.A.

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Indications & Clinical Uses

Ibuprofen acts as a non‑selective cyclooxygenase inhibitor and is indicated for conditions involving pain, fever, or inflammation.

  • Pain: provides analgesic effect to reduce mild to moderate pain.
  • Fever: lowers elevated body temperature.
  • Inflammation: decreases swelling and redness associated with inflammatory processes.

How It Works

  • Ibuprofen inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, reducing the conversion of arachidonic acid to prostaglandins. Lower prostaglandin levels diminish peripheral sensitization of nociceptors, lower the hypothalamic set‑point for temperature, and limit the inflammatory cascade, resulting in analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Ibuprofen may cause a range of adverse reactions, which are grouped by frequency and severity.

Common Side Effects

  • Dyspepsia or stomach upset.
  • Nausea or vomiting.
  • Headache.
  • Dizziness.
  • Mild skin rash.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment.
  • Severe allergic reactions such as anaphylaxis.
  • Hepatotoxicity with elevated liver enzymes.
  • Cardiovascular events including myocardial infarction or stroke.

Precautions & Warnings

When using Ibuprofeno Cinfamed, consider the following safety measures.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding before initiating therapy.
  • Monitor renal function: check kidney status, especially in patients with dehydration or pre‑existing renal disease.
  • Evaluate cardiovascular risk: use the lowest effective dose in patients with heart disease or hypertension.
  • Use lowest effective dose: limit duration to reduce the likelihood of adverse events.
  • Avoid in known hypersensitivity: discontinue immediately if allergic reactions occur.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofeno Cinfamed can interact with several medication classes; awareness helps prevent complications.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • Diuretics: may reduce renal clearance of ibuprofen, affecting kidney function.
  • Methotrexate: potential for increased methotrexate toxicity due to reduced renal elimination.

Frequently Asked Questions

Ibuprofeno Cinfamed contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, lower fever, and reduce inflammation caused by conditions such as musculoskeletal injuries, dental pain, and febrile illnesses. It is prescribed for adults and, when appropriate, for children under medical supervision.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the synthesis of prostaglandins, which are mediators that promote pain, fever, and inflammation. By lowering prostaglandin levels, ibuprofen produces analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Ibuprofeno Cinfamed is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and response to therapy. Healthcare professionals tailor the regimen to achieve the desired effect while minimizing potential risks.

Safety data for ibuprofen in pregnancy and lactation are limited. It is generally advised to avoid NSAIDs, including ibuprofen, during the third trimester of pregnancy and to discuss any use while breastfeeding with a healthcare provider, who can weigh potential benefits against risks.

To order Ibuprofeno Cinfamed, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Ibuprofeno Cinfamed offers the same active ingredient as other ibuprofen‑based products, providing a well‑characterized safety and efficacy profile. Compared with stronger NSAIDs such as diclofenac or naproxen, ibuprofen generally has a shorter half‑life and may be associated with a lower risk of certain cardiovascular events, though individual response varies.

Store Ibuprofeno Cinfamed at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Ibuprofeno Cinfamed is intended for oral administration. The tablets (or other oral dosage form) should be swallowed whole with a full glass of water, preferably with food or milk to lessen gastrointestinal irritation, unless the prescriber provides alternative instructions.

Serious risks include gastrointestinal bleeding or ulcer perforation, acute kidney injury, severe allergic reactions such as anaphylaxis, and increased cardiovascular events like heart attack or stroke. Patients should seek immediate medical attention if they experience symptoms such as black stools, sudden loss of kidney function, rash with swelling, or chest pain.

Individuals with a known hypersensitivity to ibuprofen or any other NSAID, those with active gastrointestinal ulcers, severe renal or hepatic impairment, uncontrolled heart failure, or who are in the third trimester of pregnancy should avoid using Ibuprofeno Cinfamed unless specifically directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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