Product image of Ibuprofeno Codramol (Ibuprofen) supplied by GNH India

Ibuprofeno Codramol

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Codramol (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Codramol, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It reduces pain, fever and inflammation in adults and children when prescribed by a healthcare professional. The medication works by inhibiting cyclooxygenase enzymes, which lowers prostaglandin production and thereby alleviates mild to moderate discomfort associated with various conditions.

GNH India supplies Ibuprofeno Codramol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance.

Manufacturer / TM Owner

Farmalider, S.A.

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Indications & Clinical Uses

Ibuprofen is an NSAID that acts on inflammatory pathways to relieve symptoms.

  • Pain: provides relief from mild to moderate acute pain such as headache, dental pain, or musculoskeletal discomfort.
  • Fever: reduces elevated body temperature associated with infections or inflammatory states.
  • Inflammation: alleviates swelling and stiffness in conditions like osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. This reduction in prostaglandin synthesis diminishes peripheral sensitization, leading to decreased pain perception, lower fever, and reduced inflammation at the site of tissue injury.

Side Effects

Common side effects are generally mild and transient.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or mild itching.
  • Elevated blood pressure in some patients.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment or failure.
  • Severe allergic reactions such as anaphylaxis.
  • Hepatotoxicity or elevated liver enzymes.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

When using Ibuprofeno Codramol, consider the following precautions.

  • Assess renal function: adjust use in patients with impaired kidney function.
  • Monitor gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Use caution in cardiovascular disease: NSAIDs may increase risk of thrombotic events.
  • Avoid in late pregnancy: NSAIDs are contraindicated in the third trimester.
  • Review drug interactions: check concomitant medications for potential additive effects.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofeno Codramol can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • SSRIs or SNRIs: heightened risk of bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may impair renal function when combined.
  • Methotrexate: reduced clearance may raise toxicity.

Frequently Asked Questions

Ibuprofeno Codramol contains ibuprofen, an NSAID that is used to relieve mild to moderate pain, reduce fever, and decrease inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, and inflammatory joint disorders.

Ibuprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. Lower prostaglandin levels reduce the signals that cause pain, fever, and inflammation.

The appropriate dose of Ibuprofeno Codramol is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester because of potential fetal complications, and use during early pregnancy or while breastfeeding should be discussed with a healthcare provider.

To order Ibuprofeno Codramol, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofeno Codramol delivers ibuprofen, which has a well‑established efficacy and safety profile comparable to other NSAIDs such as naproxen or diclofenac. Differences may include dosing frequency, gastrointestinal tolerability, and specific drug‑interaction profiles, which clinicians consider when selecting therapy.

Ibuprofeno Codramol should be stored at ambient temperature, below 25 °C, in its original packaging. It must be kept away from moisture, direct sunlight, and excessive heat to maintain product stability.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce the chance of stomach upset. The exact administration schedule is set by the prescriber.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, acute kidney injury, and rare but severe skin reactions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience signs of these conditions.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, late‑stage pregnancy, or those taking certain anticoagulants without medical supervision should avoid using Ibuprofeno Codramol.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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