Product image of Ibuprofeno Codramol (Ibuprofen) supplied by GNH India

Ibuprofeno Codramol

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Codramol (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Codramol, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve mild to moderate pain, reduce fever, and manage inflammatory conditions such as arthritis in adults and adolescents.
GNH India supplies Ibuprofeno Codramol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Nutra Essential Otc, S.L.

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Indications & Clinical Uses

Ibuprofen acts systemically to reduce inflammation and pain by inhibiting prostaglandin synthesis, making it useful across several common conditions.

  • Mild to moderate pain: provides analgesia for headaches, dental pain, musculoskeletal aches, and postoperative discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammatory conditions such as arthritis: decreases joint swelling and improves mobility in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin levels diminish inflammation, lower pain‑signal transmission, and reset the hypothalamic set‑point for body temperature, resulting in analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or mild itching.
  • Elevated blood pressure in susceptible individuals.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Acute renal impairment or failure.
  • Severe allergic reactions, including anaphylaxis.
  • Hepatotoxicity with marked liver enzyme elevation.
  • Cardiovascular events such as myocardial infarction or stroke, especially with high‑dose or prolonged use.

Precautions & Warnings

Before using Ibuprofeno Codramol, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcer disease or recent GI bleeding.
  • Monitor renal function: use cautiously in individuals with chronic kidney disease or dehydration.
  • Avoid concomitant anticoagulants: increased risk of bleeding when combined with warfarin or similar agents.
  • Use the lowest effective dose for the shortest duration needed to control symptoms.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofeno Codramol may alter the effect of several medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: increased risk of ulceration and bleeding.
  • Lithium: possible increase in lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors or ARBs: may diminish antihypertensive effect and affect renal function.

  • Diuretics: potential for reduced renal perfusion.
  • SSRIs or SNRIs: modest increase in bleeding tendency.
  • Antihypertensive drugs: possible attenuation of blood‑pressure control.
  • Antidiabetic agents: may affect glycemic control.

Frequently Asked Questions

Ibuprofeno Codramol contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, lower fever, and reduce inflammation associated with conditions such as arthritis, dental pain, and musculoskeletal aches.

Ibuprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which prevents the formation of prostaglandins. Lower prostaglandin levels reduce inflammation, diminish pain signaling, and help reset the body’s temperature regulation center, providing analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Ibuprofeno Codramol is determined by a prescriber based on the patient’s age, weight, clinical condition, and response to therapy. Patients should follow the healthcare professional’s instructions and never exceed the recommended amount.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester and used only if clearly needed in earlier stages. Breastfeeding mothers should consult a healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ibuprofeno Codramol offers a balance of analgesic, antipyretic, and anti‑inflammatory activity similar to other NSAIDs such as naproxen or diclofenac. Differences may include dosing frequency, gastrointestinal tolerability, and specific cardiovascular or renal risk profiles, which are evaluated by the prescribing clinician.

Store Ibuprofeno Codramol at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Ibuprofeno Codramol is taken orally, usually with a full glass of water. It may be taken with or without food, although taking it with food can help reduce gastrointestinal discomfort.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, acute kidney injury, and increased cardiovascular events like heart attack or stroke, especially with high doses or prolonged therapy.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcer or bleeding, severe heart failure, advanced renal impairment, or those taking certain anticoagulants should avoid using Ibuprofeno Codramol unless advised otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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