Product image of Ibuprofeno Codramol Farmalider (Ibuprofen) supplied by GNH India

Ibuprofeno Codramol Farmalider

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Codramol Farmalider (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Codramol Farmalider, is a nonsteroidal anti-inflammatory drug presented as an oral formulation for oral use. It treats mild to moderate pain, fever, and inflammatory conditions such as arthritis in adults.

GNH India supplies Ibuprofeno Codramol Farmalider as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Farmalider, S.A.

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Indications & Clinical Uses

Ibuprofen, an NSAID, is used to manage conditions involving pain, fever, and inflammation.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, and musculoskeletal discomfort.
  • Fever: lowers elevated body temperature in febrile states.
  • Inflammatory arthritis: reduces joint inflammation and stiffness associated with rheumatoid or osteoarthritis.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This inhibition decreases the synthesis of prostaglandins, which are mediators of inflammation, pain, and fever, thereby producing analgesic, antipyretic, and anti‑inflammatory actions.

Side Effects

Adverse reactions may occur with ibuprofen use and vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort or dyspepsia.
  • Nausea or vomiting.
  • Headache.
  • Dizziness.
  • Mild skin rash.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Acute renal impairment.
  • Severe allergic reactions such as anaphylaxis.
  • Hepatotoxicity.
  • Thrombotic cardiovascular events.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess renal function: monitor patients with existing kidney disease.
  • Avoid in active peptic ulcer disease: increased risk of gastrointestinal bleeding.
  • Use caution with anticoagulants: potential for additive bleeding risk.
  • Limit use in pregnancy, especially the third trimester: possible fetal complications.
  • Do not administer to children under 12 years unless specifically prescribed.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function.
  • Diuretics: risk of renal impairment when combined.
  • Lithium: ibuprofen can raise lithium serum levels.

Frequently Asked Questions

Ibuprofeno Codramol Farmalider contains ibuprofen, an NSAID indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammatory disorders such as arthritis. It is commonly prescribed for headaches, dental pain, musculoskeletal aches, and febrile episodes.

Ibuprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for prostaglandin production. Lower prostaglandin levels diminish inflammation, reduce the sensation of pain, and lower the hypothalamic set‑point for body temperature, thereby providing analgesic and antipyretic effects.

The appropriate dose of ibuprofen is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Ibuprofen is generally avoided during the third trimester of pregnancy because it may affect fetal cardiovascular function. Use during earlier trimesters should only occur if the prescriber deems it necessary. While limited data exist for breastfeeding, ibuprofen is excreted in small amounts in milk; mothers should consult their clinician before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Ibuprofen belongs to the NSAID class, offering both analgesic and anti‑inflammatory benefits, unlike acetaminophen which lacks anti‑inflammatory activity. Compared with stronger NSAIDs such as diclofenac, ibuprofen has a slightly lower risk of gastrointestinal complications at standard doses, but all NSAIDs share similar cautions regarding renal function and bleeding.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Do not refrigerate or freeze the tablets, and keep them out of reach of children.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may lessen gastrointestinal discomfort. Patients should swallow the tablet whole and avoid crushing or chewing unless directed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, acute kidney injury, severe allergic reactions such as anaphylaxis, and increased risk of cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they notice signs of bleeding, severe rash, or chest pain.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active peptic ulcer disease, severe heart failure, uncontrolled hypertension, or significant renal impairment should avoid ibuprofen. It is also contraindicated in the third trimester of pregnancy and should be used with caution in the elderly.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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