Product image of Ibuprofeno Farmalider S.A. (Ibuprofen) supplied by GNH India

Ibuprofeno Farmalider S.A.

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Farmalider S.A. (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Farmalider S.A., is a nonsteroidal anti-inflammatory drug presented as an oral formulation for oral use. It is employed to relieve mild to moderate pain, reduce fever, and manage inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and dysmenorrhea.

GNH India supplies Ibuprofeno Farmalider S.A. as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Customers benefit from consistent product quality, regulatory compliance, and responsive technical support.

Manufacturer / TM Owner

Farmalider, S.A.

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Indications & Clinical Uses

Ibuprofen acts systemically to reduce inflammation and pain by inhibiting cyclooxygenase enzymes, making it useful for several common conditions.

  • Mild to moderate pain: provides analgesia for headaches, dental pain, and musculoskeletal discomfort.
  • Fever: lowers elevated body temperature in adults and children.
  • Osteoarthritis and rheumatoid arthritis: alleviates joint pain and swelling associated with chronic inflammatory arthritis.
  • Dysmenorrhea: reduces menstrual cramps and associated discomfort.

How It Works

  • Ibuprofen exerts its effect through reversible inhibition of cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which catalyze the conversion of arachidonic acid to prostaglandins. By decreasing prostaglandin synthesis, it reduces peripheral sensitization of nociceptors, lowers the hypothalamic fever set‑point, and diminishes inflammatory exudate formation, resulting in analgesic, antipyretic, and anti‑inflammatory actions.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild and transient to serious and potentially life‑threatening.

Common Side Effects

  • Nausea or dyspepsia: mild gastrointestinal upset.
  • Headache: occasional mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Renal impairment: reduced kidney function or acute injury.
  • Severe allergic reactions: anaphylaxis, angioedema, or Stevens‑Johnson syndrome.

Precautions & Warnings

When prescribing ibuprofen, clinicians should evaluate patient risk factors and follow safety guidelines to minimize adverse outcomes.

  • Assess renal function: evaluate baseline creatinine in patients with kidney disease.
  • Avoid in active peptic ulcer disease: contraindicated in current gastrointestinal ulceration.
  • Use caution with anticoagulants: increased bleeding risk when combined with warfarin or similar agents.
  • Limit duration in cardiovascular disease: prolonged use may elevate risk of thrombotic events.
  • Check for hypersensitivity: discontinue if rash, angioedema, or anaphylaxis occurs.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines, altering efficacy or safety; interactions are categorized by clinical significance.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened risk of serious bleeding.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce antihypertensive effect and impair renal function.
  • Diuretics (loop or thiazide): potential for reduced diuretic efficacy and renal compromise.
  • Lithium: ibuprofen can raise lithium serum concentrations, risking toxicity.

Frequently Asked Questions

Ibuprofeno Farmalider contains ibuprofen, an NSAID that is used to relieve mild to moderate pain, reduce fever, and treat inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and dysmenorrhea. It provides analgesic, antipyretic, and anti‑inflammatory effects in adults and, when appropriate, in pediatric patients.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. Lower prostaglandin levels reduce inflammation, lower the hypothalamic set‑point for temperature, and decrease the sensitivity of pain‑receiving nerves, producing its therapeutic effects.

The appropriate dose of ibuprofen is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Dosage regimens may differ for pain, fever, or chronic inflammatory disorders, and the prescriber will provide specific instructions.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because of potential fetal cardiovascular effects, and caution is advised throughout pregnancy. It is excreted in breast milk, so nursing mothers should consult their physician before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Ibuprofen shares the core anti‑inflammatory mechanism of other NSAIDs but offers a relatively balanced COX‑1/COX‑2 inhibition profile, providing both analgesia and anti‑inflammatory action. Compared with acetaminophen, ibuprofen adds anti‑inflammatory benefits but carries a higher risk of gastrointestinal and renal effects, making choice dependent on the clinical scenario.

Store the product at room temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children. Do not use if the packaging is damaged or the tablets show signs of discoloration.

Ibuprofeno Farmalider is intended for oral administration. The tablets should be swallowed whole with a full glass of water. It can be taken with or without food; taking it with food or milk may reduce gastrointestinal discomfort for some patients.

Serious risks include gastrointestinal bleeding or ulcer perforation, acute kidney injury, severe hypersensitivity reactions such as anaphylaxis, and increased cardiovascular events like myocardial infarction or stroke, especially with high‑dose or prolonged use. Patients should be monitored for these events and discontinue use if they occur.

Ibuprofen should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active peptic ulcer disease, severe renal or hepatic impairment, uncontrolled hypertension, and in the third trimester of pregnancy. It is also contraindicated in patients receiving certain anticoagulants or other NSAIDs without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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