Product image of Ibuprofeno Generis Phar (Ibuprofen) supplied by GNH India

Ibuprofeno Generis Phar

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Generis Phar (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Generis Phar, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve pain, reduce fever, and diminish inflammation in adults and children when appropriate.
GNH India supplies Ibuprofeno Generis Phar as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Generis Farmacêutica, S.A.

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Indications & Clinical Uses

Ibuprofen acts systemically to reduce prostaglandin‑mediated inflammation and pain.

  • Pain: provides relief of mild to moderate acute pain such as headache, toothache, or musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infection or inflammatory conditions.
  • Inflammation: decreases swelling and stiffness in conditions like osteoarthritis or rheumatoid arthritis.
  • Dysmenorrhea: alleviates menstrual cramps and associated pelvic pain.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis leads to diminished inflammation, lower pain signaling, and a decreased febrile response in peripheral tissues and the hypothalamus.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort such as nausea, dyspepsia, or abdominal pain.
  • Headache or dizziness.
  • Mild skin rash or itching.
  • Elevated blood pressure in some individuals.

Serious or Rare Side Effects

  • Gastrointestinal bleeding, ulceration, or perforation.
  • Acute renal failure or worsening of chronic kidney disease.
  • Severe hypersensitivity reactions including anaphylaxis or Stevens‑Johnson syndrome.
  • Hepatotoxicity presenting as jaundice or elevated liver enzymes.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Monitor renal function: use caution in those with impaired kidney function or dehydration.
  • Use the lowest effective dose for the shortest duration needed.
  • Avoid use in the third trimester of pregnancy due to fetal risks.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can affect the activity of several other medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • ACE inhibitors or ARBs: may reduce antihypertensive effect and impair renal function.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible reduction in diuretic efficacy and renal perfusion.
  • Methotrexate: may increase methotrexate serum concentrations and toxicity.

Frequently Asked Questions

Ibuprofeno Generis Phar contains ibuprofen, which is commonly used to treat mild to moderate pain, reduce fever, and manage inflammation associated with conditions such as arthritis, dental pain, musculoskeletal injuries, and dysmenorrhea. The specific indication is determined by the prescribing clinician based on the patient’s clinical situation.

Ibuprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins. By lowering prostaglandin levels, it reduces inflammation, diminishes pain signaling, and helps lower elevated body temperature.

The appropriate dose of ibuprofen is individualized by the prescriber according to the patient’s age, weight, medical condition, and response to therapy. Healthcare professionals determine the strength, frequency, and duration that best meet the therapeutic goal while minimizing risk.

Ibuprofen should be avoided in the third trimester of pregnancy because it may affect fetal cardiovascular development. During the first and second trimesters, it may be used only if clearly needed and prescribed. Ibuprofen passes into breast milk in small amounts; short‑term use is generally considered compatible with breastfeeding, but a clinician should evaluate the risk‑benefit balance.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details (including any temperature requirements), and assists with import documentation.

Ibuprofen shares a similar mechanism of action with other non‑steroidal anti‑inflammatory drugs, such as naproxen or diclofenac, but differs in pharmacokinetic profile, dosing frequency, and individual tolerability. Compared with some NSAIDs, ibuprofen has a relatively short half‑life, which may require more frequent dosing, yet it is often preferred for its well‑established safety record at recommended doses.

Ibuprofeno Generis Phar should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

The product is intended for oral administration. It may be taken with or without food, although taking it with a meal or a glass of milk can help reduce gastrointestinal discomfort. Swallow tablets or capsules whole; do not crush or chew unless the formulation specifically permits it.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, acute kidney injury, and cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they notice signs of bleeding, severe rash, swelling, or sudden shortness of breath.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or in the third trimester of pregnancy should not use ibuprofen. Additionally, patients taking anticoagulants, certain antihypertensives, or with significant renal impairment should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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