Product image of Ibuprofeno Liderfarm (Ibuprofen) supplied by GNH India

Ibuprofeno Liderfarm

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Liderfarm (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Liderfarm, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects for the treatment of mild to moderate pain, fever and inflammatory conditions such as arthritis in adults and children where appropriate.

GNH India supplies Ibuprofeno Liderfarm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU GMP standards and provides reliable logistics for global distribution.

Manufacturer / TM Owner

Farmalider, S.A.

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Indications & Clinical Uses

  • Ibuprofen acts systemically to reduce inflammation and pain, making it useful for several common conditions.
  • Mild to moderate pain: Relieves headache, dental, musculoskeletal and postoperative pain.
  • Fever: Lowers elevated body temperature associated with infections or inflammatory states.
  • Arthritis and other inflammatory conditions: Decreases joint swelling and improves mobility in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which are key in the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis diminishes peripheral sensitisation of nociceptors, lowers the hypothalamic set‑point for temperature, and limits inflammatory exudate formation, thereby providing analgesic, antipyretic and anti‑inflammatory actions.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort or dyspepsia
  • Nausea or vomiting
  • Headache
  • Dizziness
  • Mild skin rash
  • Transient elevation of liver enzymes

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding
  • Acute renal impairment or failure
  • Hepatotoxicity
  • Severe hypersensitivity reactions (e.g., Stevens‑Johnson syndrome)
  • Cardiovascular events such as myocardial infarction or stroke
  • Anaphylaxis

Precautions & Warnings

  • When using ibuprofen, several precautions should be observed to minimise risk.
  • Assess renal function: Avoid use in severe renal impairment or dehydration.
  • Monitor gastrointestinal health: Use with caution in patients with a history of ulcer or bleeding.
  • Evaluate cardiovascular risk: Limit use in patients with established heart disease or uncontrolled hypertension.
  • Consider pregnancy and lactation: Discuss with a healthcare professional before use.
  • Avoid concomitant use with other NSAIDs or anticoagulants unless directed.
  • Store at room temperature: Keep in the original container, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Selective COX‑2 inhibitors: additive gastrointestinal toxicity.
  • High‑dose aspirin: enhanced renal toxicity.
  • Lithium: increased serum lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function.
  • Diuretics: potential for reduced renal perfusion.
  • Corticosteroids: increased risk of gastrointestinal ulceration.
  • SSRIs or SNRIs: heightened bleeding tendency.
  • Beta‑blockers: may blunt antihypertensive effect.

Frequently Asked Questions

Ibuprofeno Liderfarm contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and treat inflammatory conditions such as osteoarthritis or rheumatoid arthritis. It is suitable for adults and, when prescribed, for children who require analgesic or antipyretic therapy.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, it reduces inflammation, diminishes pain signalling, and helps reset the hypothalamic temperature set‑point, resulting in antipyretic action.

The appropriate dose of Ibuprofeno Liderfarm is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. Patients should follow the prescriber’s instructions and the product label; no generic dosing regimen is provided here.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. Generally, ibuprofen is avoided in the third trimester because of potential fetal cardiovascular effects, and it should be used only if clearly needed during the first two trimesters. Breastfeeding mothers should consult a healthcare professional before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ibuprofeno Liderfarm (ibuprofen) offers a balance of analgesic, antipyretic and anti‑inflammatory activity with a relatively short half‑life, allowing flexible dosing. Compared with naproxen, ibuprofen has a quicker onset but may require more frequent dosing. Unlike acetaminophen, ibuprofen also reduces inflammation but carries a higher gastrointestinal risk.

Store the tablets at room temperature, preferably below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

Ibuprofeno Liderfarm is taken orally with a full glass of water. It may be taken with food or milk to lessen possible stomach irritation. The tablet should be swallowed whole; it should not be crushed, chewed, or dissolved unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, acute kidney injury, severe allergic reactions such as Stevens‑Johnson syndrome, and increased cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they notice signs of bleeding, severe rash, or chest pain.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration, severe heart failure, uncontrolled hypertension, or advanced renal or hepatic disease should avoid using Ibuprofeno Liderfarm unless directed by a physician. It is also contraindicated in patients taking certain anticoagulants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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