Product image of Ibuprofeno Neforan (Ibuprofen) supplied by GNH India

Ibuprofeno Neforan

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Neforan (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Neforan, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is used to relieve mild to moderate pain, reduce fever, and manage inflammatory conditions such as arthritis.

GNH India supplies Ibuprofeno Neforan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution.

Manufacturer / TM Owner

Towa Pharmaceutical S.A.

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Indications & Clinical Uses

Ibuprofeno Neforan, an NSAID, is indicated for conditions that involve pain, fever, or inflammation.

  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, musculoskeletal discomfort, and menstrual cramps.
  • Fever: reduces elevated body temperature associated with infections or inflammatory processes.
  • Osteoarthritis: alleviates joint pain and improves functional mobility.
  • Rheumatoid arthritis: helps control inflammatory joint swelling and pain.
  • Dental procedures: manages postoperative pain and inflammation after extractions or surgeries.

How It Works

  • Ibuprofeno Neforan exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This inhibition reduces the conversion of arachidonic acid to prostaglandins, thereby decreasing the synthesis of mediators that cause inflammation, pain, and fever. The reduced prostaglandin levels lead to the observed therapeutic outcomes in various painful and inflammatory conditions.

Side Effects

Ibuprofeno Neforan may cause adverse reactions; they are categorized by frequency.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or mild abdominal pain.
  • Headache: transient tension‑type headache.
  • Dizziness: occasional light‑headedness.
  • Rash: mild skin erythema or itching.
  • Elevated liver enzymes: transient increase in hepatic transaminases.
  • Fluid retention: mild peripheral edema.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe renal impairment or acute kidney injury.
  • Anaphylaxis or severe allergic reactions.
  • Hepatotoxicity with marked liver enzyme elevation.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Blood dyscrasias: thrombocytopenia or leukopenia.

Precautions & Warnings

Before using Ibuprofeno Neforan, consider the following precautions.

  • Assess renal function: avoid or adjust use in patients with severe renal impairment.
  • Monitor gastrointestinal health: use cautiously in individuals with a history of ulcers or bleeding.
  • Evaluate cardiovascular risk: limit use in patients with established heart disease or high thrombotic risk.
  • Check for hypersensitivity: discontinue if allergic reactions to ibuprofen or other NSAIDs occur.
  • Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding.
  • Store at room temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofeno Neforan can interact with other medicines; interactions are grouped by clinical significance.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Selective COX‑2 inhibitors: additive renal toxicity.
  • High‑dose aspirin: heightened gastrointestinal ulcer risk.
  • Lithium: elevated serum lithium concentrations.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible decline in renal function.
  • Diuretics: risk of electrolyte imbalance and reduced renal perfusion.
  • SSRIs or SNRIs: increased bleeding tendency.
  • Corticosteroids: synergistic risk of gastrointestinal ulceration.
  • Cyclosporine: enhanced nephrotoxic potential.

Frequently Asked Questions

Ibuprofeno Neforan is a formulation of ibuprofen that is used to relieve mild to moderate pain, lower fever, and reduce inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, dental procedures, and other inflammatory disorders.

Ibuprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin production, it diminishes the signals that cause pain, fever, and inflammation.

The appropriate dose of Ibuprofeno Neforan is determined by the prescribing healthcare professional based on the patient’s age, weight, medical condition, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester and used only when clearly needed in earlier stages. Breastfeeding mothers should consult their doctor, as ibuprofen does pass into milk in small amounts.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Ibuprofeno Neforan (ibuprofen) and naproxen belong to the same NSAID class but differ in half‑life and dosing frequency. Ibuprofen typically requires multiple daily doses, while naproxen has a longer duration of action, allowing once‑ or twice‑daily dosing. Both share similar efficacy for pain and inflammation, though individual tolerability and specific risk profiles may guide selection.

Store Ibuprofeno Neforan at room temperature, below 25 °C, in the original packaging. Keep the product away from moisture, direct sunlight, and excessive heat. Ensure the container is tightly closed to maintain product stability.

Ibuprofeno Neforan is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort. Follow the prescriber’s instructions regarding timing and whether it should be taken on an empty stomach.

Serious risks include gastrointestinal bleeding or ulceration, severe kidney injury, cardiovascular events such as heart attack or stroke, and life‑threatening allergic reactions like anaphylaxis. Patients should be monitored for signs of these conditions and seek immediate medical attention if they occur.

Individuals with known hypersensitivity to ibuprofen or any other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, severe renal or hepatic impairment, and patients in the third trimester of pregnancy should avoid using Ibuprofeno Neforan unless specifically directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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