Product image of Ibuprofeno + Paracetamol Vale (Ibuprofen, Paracetamol) supplied by GNH India

Ibuprofeno + Paracetamol Vale

Active Ingredient:
Ibuprofen, Paracetamol
Origin:
EU

Ibuprofeno + Paracetamol Vale (Ibuprofen, Paracetamol)

Ibuprofen and Paracetamol, the active ingredients in Ibuprofeno + Paracetamol Vale, are NSAID and analgesic agents presented as an intravenous solution for intravenous use. They provide pain relief, fever reduction, and anti‑inflammatory effects in adult patients requiring rapid therapeutic action.

GNH India supplies Ibuprofeno + Paracetamol Vale as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Vale Pharmaceuticals Limited

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Indications & Clinical Uses

Ibuprofeno + Paracetamol Vale combines ibuprofen and paracetamol to address pain, fever and inflammation.

  • Pain: rapid analgesia for acute or postoperative discomfort.
  • Fever: effective reduction of elevated body temperature.
  • Inflammation: diminishes inflammatory response in musculoskeletal conditions.
  • Post‑operative pain: provides swift relief after surgical procedures.

How It Works

  • Ibuprofen inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, decreasing prostaglandin synthesis and thereby reducing inflammation and pain. Paracetamol acts centrally to inhibit COX activity and modulate the endocannabinoid system, producing analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Headache: transient cranial discomfort.
  • Injection site pain: local irritation at the IV site.
  • Dizziness: occasional light‑headed sensation.
  • Mild hypotension: transient drop in blood pressure.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis): respiratory distress, rash, swelling.
  • Gastrointestinal bleeding: occult or overt bleeding, especially with concomitant NSAIDs.
  • Renal impairment: acute kidney injury in susceptible patients.
  • Hepatic failure: rare but possible with excessive paracetamol exposure.
  • Stevens‑Johnson syndrome: severe skin and mucous membrane reaction.

Precautions & Warnings

When using Ibuprofeno + Paracetamol Vale, consider the following precautions:

  • Assess renal function: monitor creatinine and urine output before and during therapy.
  • Avoid in active peptic ulcer disease: increased risk of gastrointestinal bleeding.
  • Use with caution in asthma: potential for bronchospasm.
  • Limit use in hepatic impairment: monitor liver enzymes regularly.
  • Avoid concomitant anticoagulants: heightened bleeding tendency.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Ibuprofeno + Paracetamol Vale may interact with other medicines as follows:

Major Interactions (Avoid)

  • Concurrent use with other NSAIDs: increased gastrointestinal and renal toxicity.
  • Combination with anticoagulants (e.g., warfarin, heparin): heightened bleeding risk.
  • Co‑administration with high‑dose paracetamol: risk of hepatotoxicity.

Moderate Interactions (Monitor Closely)

  • Use with ACE inhibitors or diuretics: may reduce renal perfusion.
  • Concurrent corticosteroids: increased ulcer risk.
  • Interaction with lithium: may elevate lithium serum levels.

Frequently Asked Questions

Ibuprofeno + Paracetamol Vale is an intravenous formulation that combines ibuprofen and paracetamol to provide rapid relief of pain, reduce fever, and lessen inflammation in adult patients who need prompt therapeutic effect.

Ibuprofen blocks cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, lowering prostaglandin production. This reduces inflammation, alleviates pain, and contributes to antipyretic activity as part of the combined IV solution.

The prescribed dose is determined by the treating physician based on the patient’s clinical condition, weight, and response. Dosing regimens are individualized and should follow the prescriber’s instructions.

Safety in pregnancy and lactation has not been definitively established for this intravenous combination. Healthcare providers should evaluate the risk‑benefit profile before prescribing to pregnant or nursing women.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

The combination adds paracetamol’s central analgesic and antipyretic actions to ibuprofen’s peripheral anti‑inflammatory effect, often achieving faster pain control and fever reduction than ibuprofen alone, while allowing lower individual doses of each component.

Store the intravenous solution at 2‑8 °C, keep it refrigerated, protect from light, and avoid freezing or shaking. Use aseptic technique when preparing the infusion.

The product is given by intravenous infusion under the supervision of qualified healthcare professionals. The infusion rate and volume are set according to the prescriber’s orders and patient tolerance.

Serious risks include severe allergic reactions (anaphylaxis), gastrointestinal bleeding, acute kidney injury, and rare hepatic failure. Immediate medical attention is required if any of these occur.

Patients with known hypersensitivity to ibuprofen, paracetamol, or any component of the formulation, those with active peptic ulcer disease, severe renal or hepatic impairment, and individuals on certain anticoagulants should avoid this product unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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