Product image of Ibuprofeno Pensa (Ibuprofen) supplied by GNH India

Ibuprofeno Pensa

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Pensa (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Pensa, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects for mild to moderate pain, fever and inflammatory conditions in adults and children when appropriate.
GNH India supplies Ibuprofeno Pensa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Towa Pharmaceutical S.A.

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Indications & Clinical Uses

Ibuprofeno Pensa, an NSAID, acts on prostaglandin‑mediated pathways to relieve pain and inflammation.

  • Mild to moderate pain: Provides analgesic relief for everyday aches such as headache, toothache, or musculoskeletal discomfort.
  • Fever: Reduces elevated body temperature by acting on the hypothalamic heat‑regulation center.
  • Osteoarthritis and rheumatoid arthritis: Decreases joint inflammation and improves mobility in chronic inflammatory joint diseases.
  • Dysmenorrhea: Alleviates menstrual cramps by reducing uterine prostaglandin production.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes inflammation, lowers fever, and decreases the perception of pain at peripheral and central sites.

Side Effects

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin irritation or erythema.
  • Elevated liver enzymes: asymptomatic laboratory finding.
  • Fluid retention: mild peripheral edema.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe renal impairment or acute kidney injury.
  • Anaphylactic or severe allergic reactions.
  • Hepatotoxicity with jaundice.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Assess renal function: evaluate kidney health, especially in elderly or dehydrated patients.
  • Review gastrointestinal risk: avoid in individuals with active ulcers or a history of serious GI bleeding.
  • Monitor cardiovascular status: use cautiously in patients with established heart disease.
  • Evaluate concomitant medications: check for drugs that increase bleeding risk or affect renal perfusion.
  • Avoid use in late pregnancy: discuss alternatives with a healthcare professional.
  • Store at ambient temperature below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened ulcer and bleeding risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: possible reduction in renal function.
  • Diuretics: may decrease renal perfusion and increase nephrotoxicity.
  • SSRIs: potential for increased bleeding tendency.

Frequently Asked Questions

Ibuprofeno Pensa contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and treat inflammatory conditions such as osteoarthritis, rheumatoid arthritis and menstrual cramps. It works by decreasing the production of prostaglandins that cause pain and inflammation.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the conversion of arachidonic acid into prostaglandins, which are mediators of inflammation, pain, and fever. Lower prostaglandin levels result in reduced swelling, pain perception, and body temperature.

The appropriate dose of Ibuprofeno Pensa is determined by the prescribing healthcare professional based on the patient’s age, weight, medical condition and response to therapy. Typical adult regimens range from 200 mg to 400 mg every 4‑6 hours, but exact dosing should always follow the prescriber’s instructions.

Ibuprofen is generally avoided during the third trimester of pregnancy because it may affect fetal cardiovascular function. In earlier pregnancy, it should be used only if clearly needed and prescribed. While small amounts are excreted in breast milk, nursing mothers should consult a physician before using ibuprofen to weigh benefits against potential risks.

To place an order, visit the product page on gnhindia.com and submit an enquiry with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

The most common alternative to ibuprofen is acetaminophen (paracetamol), which provides analgesic and antipyretic effects but lacks significant anti‑inflammatory activity. Compared with other NSAIDs such as naproxen or diclofenac, ibuprofen has a shorter half‑life, which may be advantageous for intermittent pain relief but may require more frequent dosing.

Ibuprofeno Pensa should be stored at ambient temperature below 25 °C. Keep the product in its original container, protect it from moisture, excessive heat and direct sunlight. Do not store in a refrigerator or freezer unless specifically instructed on the packaging.

Ibuprofeno Pensa is intended for oral administration. The tablets (or capsules) should be swallowed whole with a full glass of water, preferably with food or milk to reduce gastrointestinal irritation. Do not crush, chew, or dissolve the dosage form unless directed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulcer perforation, especially in patients with a history of ulcers or who use anticoagulants. Renal impairment can occur, particularly in dehydrated individuals or those with pre‑existing kidney disease. Cardiovascular events such as heart attack or stroke may be heightened with long‑term high‑dose use.

Ibuprofen should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or advanced renal or hepatic disease. It is also contraindicated in the third trimester of pregnancy and in patients taking certain medications such as anticoagulants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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