Product image of Ibuprofeno Pensa Pharma (Ibuprofen) supplied by GNH India

Ibuprofeno Pensa Pharma

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Pensa Pharma (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Pensa Pharma, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It reduces pain, fever and inflammation in adults and children when prescribed by a healthcare professional.

GNH India supplies Ibuprofeno Pensa Pharma as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Towa Pharmaceutical S.A.

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Indications & Clinical Uses

Ibuprofen works by inhibiting cyclo‑oxygenase enzymes, thereby reducing prostaglandin synthesis that drives pain, fever and inflammation.

  • Mild to moderate pain: provides relief from headaches, toothaches, muscle aches and postoperative discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory conditions.
  • Osteoarthritis: improves joint mobility and reduces chronic pain.
  • Rheumatoid arthritis: helps control inflammation and swelling in affected joints.
  • Dysmenorrhea: alleviates menstrual cramps and associated discomfort.

How It Works

  • Ibuprofen non‑selectively blocks cyclo‑oxygenase‑1 (COX‑1) and cyclo‑oxygenase‑2 (COX‑2) enzymes, preventing the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin levels, it diminishes peripheral sensitization of nociceptors, lowers fever set‑points in the hypothalamus, and curtails inflammatory exudate formation, resulting in analgesic, antipyretic and anti‑inflammatory effects.

Side Effects

Ibuprofen may cause a range of adverse reactions, from mild to severe. Patients should be aware of both common and less frequent side effects.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or heartburn.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin irritation or itching.
  • Elevated blood pressure: modest increase in some individuals.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Renal impairment: reduced kidney function or acute failure.
  • Hepatotoxicity: liver enzyme elevations or hepatitis.
  • Severe allergic reactions: angioedema, anaphylaxis.
  • Cardiovascular events: increased risk of myocardial infarction or stroke in high‑risk patients.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Cardiovascular risk: avoid in patients with uncontrolled hypertension or recent heart events.
  • Gastrointestinal history: use cautiously if there is a history of ulcers or bleeding.
  • Renal function: monitor kidney function in patients with chronic kidney disease.
  • Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding.
  • Concomitant medications: review all current drugs for potential interactions.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: additive cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce antihypertensive effect and impair renal function.
  • Diuretics: potential for decreased kidney perfusion.
  • Lithium: ibuprofen can raise serum lithium levels, requiring monitoring.

Frequently Asked Questions

Ibuprofeno Pensa Pharma contains ibuprofen, an NSAID indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and dysmenorrhea. It is prescribed by healthcare professionals based on individual patient needs.

Ibuprofen inhibits the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which are responsible for converting arachidonic acid into prostaglandins. By lowering prostaglandin production, ibuprofen reduces pain signaling, lowers fever by acting on the hypothalamic heat‑regulation center, and diminishes inflammation at the site of tissue injury.

The appropriate dose of ibuprofen is determined by the prescribing clinician based on the patient’s age, weight, medical condition, and response to therapy. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

Ibuprofen should be used during pregnancy only if clearly needed and prescribed by a qualified healthcare provider, especially after the first trimester. It is generally discouraged in the third trimester due to potential fetal risks. While small amounts pass into breast milk, lactating mothers should consult their physician before using ibuprofen.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details (including any cold‑chain requirements) and required import documentation.

Ibuprofen is a non‑selective NSAID with a relatively short half‑life, offering effective analgesic, antipyretic and anti‑inflammatory actions. Compared with aspirin, it has less antiplatelet activity, and unlike selective COX‑2 inhibitors, it carries a lower cardiovascular risk but a higher gastrointestinal risk. Choice of NSAID depends on the patient’s comorbidities and risk profile.

Ibuprofeno Pensa Pharma should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture, heat and direct sunlight. Do not store in bathrooms or near sources of humidity.

The product is supplied as oral tablets intended for swallowing with a full glass of water. It may be taken with or without food; however, taking it with food can reduce gastrointestinal discomfort. The tablet should be used exactly as prescribed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, especially with prolonged use or in high‑risk patients; renal impairment that can lead to acute kidney injury; hepatotoxicity; and increased cardiovascular events such as heart attack or stroke in individuals with existing cardiovascular disease. Patients should be monitored for these complications.

Ibuprofen is contraindicated in individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, severe renal or hepatic impairment, and patients in the third trimester of pregnancy. Caution is also advised for patients with uncontrolled hypertension, heart failure, or a history of cardiovascular events.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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