Product image of Ibuprofeno/Pseudoefedrina Nutra Essential (Pseudoephedrine Hydrochloride, Ibuprofen) supplied by GNH India

Ibuprofeno/Pseudoefedrina Nutra Essential

Active Ingredient:
Pseudoephedrine Hydrochloride, Ibuprofen
Origin:
EU

Ibuprofeno/Pseudoefedrina Nutra Essential (Pseudoephedrine Hydrochloride, Ibuprofen)

Ibuprofen and pseudoephedrine hydrochloride, the active ingredients in Ibuprofeno/Pseudoefedrina Nutra Essential, are an NSAID and a sympathomimetic nasal decongestant presented as an oral tablet for oral use. They are indicated for relief of mild to moderate pain, fever and nasal congestion in adults and children when appropriate.
GNH India supplies Ibuprofeno/Pseudoefedrina Nutra Essential as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Nutra Essential Otc, S.L.

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Indications & Clinical Uses

Ibuprofen/pseudoephedrine combines an NSAID with a decongestant to address common upper‑respiratory and pain symptoms.

  • Mild to moderate pain: reduces pain intensity by inhibiting prostaglandin synthesis.
  • Fever: lowers elevated body temperature through anti‑inflammatory action.
  • Nasal congestion: relieves blockage by vasoconstricting nasal mucosal vessels.

How It Works

  • Ibuprofen blocks cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing prostaglandin production and providing analgesic and antipyretic effects. Pseudoephedrine hydrochloride stimulates α‑adrenergic receptors on nasal mucosal blood vessels, causing vasoconstriction that reduces swelling and improves airflow.

Side Effects

Common Side Effects

  • Gastrointestinal discomfort such as nausea or dyspepsia.
  • Headache or dizziness.
  • Insomnia or nervousness.
  • Elevated blood pressure.
  • Dry mouth.
  • Mild rash.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe allergic reactions including anaphylaxis.
  • Cardiovascular events such as hypertension crisis.
  • Cardiac arrhythmias.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatic or renal impairment.

Precautions & Warnings

Before using this combination, consider the following precautions:

  • Pregnancy: consult a healthcare professional; safety data are limited.
  • Cardiovascular disease: pseudoephedrine may increase blood pressure or heart rate.
  • History of gastric ulcer or GI bleeding: ibuprofen may exacerbate these conditions.
  • Kidney or liver impairment: monitor function and adjust use as needed.
  • Concomitant medications: review potential drug interactions with a pharmacist or physician.

Store at ambient temperature: keep in the original container, protect from moisture and direct heat.

Avoid Interactions

When prescribing Ibuprofen/Pseudoephedrine, be aware of potential drug interactions.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.
  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Lithium: pseudoephedrine may raise lithium serum levels.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may blunt pseudoephedrine’s decongestant effect.
  • Diuretics: can enhance pseudoephedrine‑induced blood pressure changes.
  • Antihypertensives: may reduce overall blood pressure control.
  • Certain antihistamines: may increase central nervous system stimulation.

Frequently Asked Questions

Ibuprofeno/Pseudoefedrina Nutra Essential is an over‑the‑counter oral tablet that combines ibuprofen, an NSAID, with pseudoephedrine, a nasal decongestant. It is used to relieve mild to moderate pain, reduce fever, and alleviate nasal congestion or sinus pressure associated with colds, flu, or allergic rhinitis.

Ibuprofen inhibits the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are key steps in prostaglandin synthesis. By lowering prostaglandin levels, ibuprofen reduces inflammation, pain perception, and fever, providing analgesic and antipyretic effects.

The appropriate dose of Ibuprofeno/Pseudoefedrina Nutra Essential is determined by a qualified healthcare professional based on the patient’s age, weight, medical history, and the severity of symptoms. The prescriber will provide specific dosing instructions on the product label.

Safety in pregnancy and lactation has not been fully established for the combination. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using this product.

To request a supply, visit the product page on gnhindia.com, enter the desired quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with single‑ingredient ibuprofen tablets, the combination adds a decongestant effect, making it useful when pain or fever co‑exists with nasal congestion. Unlike pure decongestants, it also offers analgesic and antipyretic benefits. However, the added pseudoephedrine may increase blood pressure, so patients with cardiovascular concerns may prefer an ibuprofen‑only product.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and direct sunlight. Do not store in bathrooms or near heat sources, and keep out of reach of children.

The tablet is taken orally with a full glass of water. It may be taken with or without food, but taking it with food can reduce gastrointestinal discomfort. Follow the dosing schedule prescribed by the healthcare professional and do not exceed the recommended number of tablets per day.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and hypertensive crises or cardiovascular events triggered by pseudoephedrine. Patients should seek immediate medical attention if they experience severe stomach pain, vomiting blood, rash, difficulty breathing, or a sudden rise in blood pressure.

Individuals with known hypersensitivity to ibuprofen, other NSAIDs, or pseudoephedrine should not use this product. It is also contraindicated in patients with uncontrolled hypertension, severe coronary artery disease, recent myocardial infarction, or those taking monoamine oxidase inhibitors. Pregnant women, especially in the third trimester, and nursing mothers should consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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