Product image of Ibuprofeno Ratiopharm (Ibuprofen) supplied by GNH India

Ibuprofeno Ratiopharm

Active Ingredient:
Ibuprofen
Origin:
EU

Ibuprofeno Ratiopharm (Ibuprofen)

Ibuprofen, the active ingredient in Ibuprofeno Ratiopharm, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It is used to relieve pain, reduce fever, and diminish inflammation in adults and children when appropriate.

GNH India supplies Ibuprofeno Ratiopharm as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ratiopharm-Comercio E Industria De Produtos Farmaceuticos Lda

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Indications & Clinical Uses

Ibuprofen acts as an analgesic, antipyretic and anti‑inflammatory agent by inhibiting prostaglandin synthesis.

  • Pain: reduces mild to moderate pain such as headache, dental pain, musculoskeletal aches and menstrual cramps.
  • Fever: lowers elevated body temperature associated with infections or inflammatory conditions.
  • Inflammation: diminishes swelling and discomfort in conditions like arthritis, sprains and soft‑tissue injuries.

How It Works

  • Ibuprofen inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin production, it decreases inflammation, lowers the hypothalamic set‑point for temperature, and diminishes the sensitization of nociceptors, resulting in analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Ibuprofen may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea: mild stomach upset or queasiness.
  • Dyspepsia: indigestion or heartburn.
  • Headache: transient head pain.
  • Dizziness: feeling light‑headed.
  • Rash: mild skin irritation.
  • Diarrhea: loose stools.

Serious or Rare Side Effects

  • Gastrointestinal ulcer or bleeding: severe stomach or intestinal bleeding.
  • Renal impairment: reduced kidney function or failure.
  • Hypersensitivity reactions: including anaphylaxis or angioedema.
  • Cardiovascular events: increased risk of heart attack or stroke.
  • Hepatotoxicity: elevated liver enzymes or liver injury.
  • Stevens‑Johnson syndrome: severe skin and mucous membrane reaction.

Precautions & Warnings

When using ibuprofen, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or history of GI bleeding.
  • Use lowest effective dose: limit duration and dose to the minimum needed for symptom control.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Caution in renal or hepatic disease: monitor kidney and liver function regularly.
  • Avoid concomitant anticoagulants: increased bleeding risk when combined with warfarin or similar agents.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: increased risk of GI ulceration.
  • ACE inhibitors or ARBs: potential reduction in renal function.
  • Lithium: elevated lithium serum levels.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible reduction in antihypertensive effect.
  • Methotrexate: decreased clearance leading to toxicity.
  • SSRIs: modest increase in bleeding tendency.
  • Oral hypoglycemics: may affect blood glucose control.
  • Antihypertensives: possible attenuation of blood pressure‑lowering effect.

Frequently Asked Questions

Ibuprofeno Ratiopharm contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, lower fever, and reduce inflammation associated with conditions such as headaches, dental pain, musculoskeletal injuries, arthritis, and febrile illnesses.

Ibuprofen works by inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, it diminishes inflammation, reduces the hypothalamic set‑point for temperature, and lessens the sensitivity of pain receptors.

The appropriate dose of Ibuprofeno Ratiopharm is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and response to therapy. Dosage instructions should always follow the healthcare professional’s recommendation and the product labeling.

Ibuprofen is generally not recommended during the third trimester of pregnancy because it may affect fetal cardiovascular function. Use during the first two trimesters should only be under medical advice. Ibuprofen passes into breast milk in small amounts, so nursing mothers should consult a healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ibuprofen belongs to the NSAID class, offering both analgesic and anti‑inflammatory effects, unlike acetaminophen which provides pain relief without significant anti‑inflammatory action. Compared with stronger NSAIDs such as diclofenac, ibuprofen generally has a more favorable gastrointestinal safety profile when used at recommended doses.

Ibuprofeno Ratiopharm tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original packaging, protect from moisture, heat, and direct sunlight to maintain potency throughout the shelf life.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food or milk may reduce the likelihood of gastrointestinal discomfort.

Serious risks include gastrointestinal bleeding or ulceration, renal impairment, severe allergic reactions such as anaphylaxis, and an increased risk of cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe renal or hepatic disease, uncontrolled hypertension, or who are in the third trimester of pregnancy should avoid using this product unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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